E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade.

Abstract
Pentavalent vanadium (metavanadate salt) toxicity is a challenging environmental hazard that affects living organisms. Studies have shown that plants play important roles in protecting against heavy metal toxicity. This study was designed to evaluate the protective activity of ethanolic extracts of Grewia carpinifolia leaves following vanadium toxicity.
Twenty five male Swiss mice were randomly divided into five groups (A–E) of five rats each. Group A rats served as control and were given distilled water, Group B was administered with sodium metavanadate and a known antioxidant agent; α-tocopherol, Groups C and D were administered with sodium metavanadate and ethanolic extract of Grewia carpinifolia leaves orally at 100 and 200 mg/kg body weight respectively while Group E was administered with only sodium metavanadate.
After a daily single oral dosing for seven days, changes in haematology and serum biochemistry parameters were analysed. Sodium metavanadate caused a significant decrease (p≤0.05) in haematocrit levels, haemoglobin (Hb) concentration, white blood cell count, neutrophil count and serum cholesterol level. A significant (p≤0.05) lymphocytosis was also observed in the group administered with sodium metavanadate alone. G. carpinifolia extract given concomitantly with sodium metavanadate was able to restore PCV, Hb concentrations and serum total protein to levels comparable with the control and standard groups. Grewia carpinifolia also significantly reduced the elevated serum levels of AST and ALT after vanadium induced hepatotoxicity. Our findings suggest that G. carpinifolia extract protected against the toxicity induced by vanadium; the plant extract at 200 mg/kg however appear to offer a better protection.

Key words: vanadium, Grewia carpinifolia, haematology, serum biochemistry, Swiss mice


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Olamide E. Adebiyi
Articles by Ayobami D. Obisesan
Articles by Funsho O. Olayemi
Articles by James O. Olopade
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. 2015; 47(1): 24-31. doi:10.5455/ajvs.189645


Web Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. https://www.alexjvs.com/?mno=189645 [Access: December 03, 2023]. doi:10.5455/ajvs.189645


AMA (American Medical Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. 2015; 47(1): 24-31. doi:10.5455/ajvs.189645



Vancouver/ICMJE Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. (2015), [cited December 03, 2023]; 47(1): 24-31. doi:10.5455/ajvs.189645



Harvard Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade (2015) Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS, 47 (1), 24-31. doi:10.5455/ajvs.189645



Turabian Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. 2015. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. Alexandria Journal of Veterinary Sciences, 47 (1), 24-31. doi:10.5455/ajvs.189645



Chicago Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. "Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity." Alexandria Journal of Veterinary Sciences 47 (2015), 24-31. doi:10.5455/ajvs.189645



MLA (The Modern Language Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. "Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity." Alexandria Journal of Veterinary Sciences 47.1 (2015), 24-31. Print. doi:10.5455/ajvs.189645



APA (American Psychological Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade (2015) Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. Alexandria Journal of Veterinary Sciences, 47 (1), 24-31. doi:10.5455/ajvs.189645





Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

  • Most Cited Articles
    Most Cited Articles