Abstract
The objective of this study was to investigate the protective effect of dietary natural sorbent-Humate (0.2%) and Hydrated sodium calcium aluminosilicate (HSCAS) (0.5%) on the prevention of aflatoxin (AF) toxicity in the broiler chicken 7-35 days of age. Two hundred and forty broiler chicks were randomly divided into four treatment groups of 4 replicates (each contained 15 chicks). While chicks in group 1 were fed a basal diet free of toxin (control), group 2 chicks were fed a basal diet contaminated with 1ppm AF, the other two groups 3 and 4 were fed contaminated basal diet supplemented with 0.2% Biofarm® Dry humate, and 0.5% HSCAS, respectively. Parameters evaluated were growth performance, some serum constituents, some organs weight, and immune response to Newcastle disease and infectious bursal disease. The results showed that, Aflatoxin (1 ppm/kg) significantly reduced feed intake, weight gain and feed efficiency. Further aflatoxin increased the relative weights of liver, kidney, gizzard and spleen, while the relative weights of thymus and bursa of Fabricius were decreased by AF. Aflatoxin toxin also reduced antibody titres against Newcastle disease and infectious bursal disease. Modified 0.2% Humate significantly (P ≤ 0.05) improved body weight, feed intake, decreased relative organ weights and improved antibody titres, bursa of Fabricius and thymus weights. Hydrated sodium calcium aluminosilicate (0.5%) showed improvement against AF. The results of our experiment showed that 0.2% Humate and 0.5% HSCAS has a positive effect on the growth of broilers. And it could have been a suitable natural supplement for growing broilers against the adverse effects of aflatoxins.

Key words: aflatoxin, broiler, adsorbent compounds, detoxification