E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy

Ahmed Sabek, Abdel-Fattah Ali, Mohamed Ramadan, Mahmoud Abouelfetouh, Atef S.A. Abd-Algalil, Eman Salah, Ahmed H. Khalil.

Abstract
This study was conducted to evaluate the effect of intramuscular (IM) administration of xylazine-nalbuphine-ketamine compared to xylazine-ketamine combination in cats subjected to median Celiotomy. Six clinically healthy adult castrated male cats (aged between 1-2 years and body weight about 1.8 to 2.6 kg) were randomly allocated into two groups; anesthesia was IM induced with xylazine-ketamine-nalbuphine (XKN group; n = 3), and xylazine-ketamine alone (XK group; n = 3). Following induction, cats underwent ventral median Celiotomy. Basic physiological parameters, analgesic and sedative scores were recorded at 5, 10, 15, 20, 30, 60, 90, and 120 min postoperatively (PO). Post-operative pain-related behaviors were also assessed. The XKN showed shorter times to lateral and sternal recumbency and longer times to first head lift and standing position than XK group (P ≤ .0.05). Sedation score revealed a significant (P ≤ 0.05) difference between both groups at 20, 30, 60 and 120 min PO. Cats in the XKN group exhibited lower post-operative pain-related behaviors than those in the XK. Nalbuphine improves sedation and postoperative analgesia of xylazine-ketamine combination in cats.

Key words: Anesthesia, Behavior, Cats, Nalbuphine, Xylazine-Ketamine


 
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How to Cite this Article
Pubmed Style

Sabek A, Ali A, Ramadan M, Abouelfetouh M, Abd-Algalil AS, Salah E, Khalil AH. Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. AJVS. 2021; 71(2): 62-69. doi:10.5455/ajvs.134252


Web Style

Sabek A, Ali A, Ramadan M, Abouelfetouh M, Abd-Algalil AS, Salah E, Khalil AH. Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. https://www.alexjvs.com/?mno=134252 [Access: April 29, 2022]. doi:10.5455/ajvs.134252


AMA (American Medical Association) Style

Sabek A, Ali A, Ramadan M, Abouelfetouh M, Abd-Algalil AS, Salah E, Khalil AH. Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. AJVS. 2021; 71(2): 62-69. doi:10.5455/ajvs.134252



Vancouver/ICMJE Style

Sabek A, Ali A, Ramadan M, Abouelfetouh M, Abd-Algalil AS, Salah E, Khalil AH. Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. AJVS. (2021), [cited April 29, 2022]; 71(2): 62-69. doi:10.5455/ajvs.134252



Harvard Style

Sabek, A., Ali, . A., Ramadan, . M., Abouelfetouh, . M., Abd-Algalil, . A. S., Salah, . E. & Khalil, . A. H. (2021) Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. AJVS, 71 (2), 62-69. doi:10.5455/ajvs.134252



Turabian Style

Sabek, Ahmed, Abdel-Fattah Ali, Mohamed Ramadan, Mahmoud Abouelfetouh, Atef S.A. Abd-Algalil, Eman Salah, and Ahmed H. Khalil. 2021. Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. Alexandria Journal of Veterinary Sciences, 71 (2), 62-69. doi:10.5455/ajvs.134252



Chicago Style

Sabek, Ahmed, Abdel-Fattah Ali, Mohamed Ramadan, Mahmoud Abouelfetouh, Atef S.A. Abd-Algalil, Eman Salah, and Ahmed H. Khalil. "Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy." Alexandria Journal of Veterinary Sciences 71 (2021), 62-69. doi:10.5455/ajvs.134252



MLA (The Modern Language Association) Style

Sabek, Ahmed, Abdel-Fattah Ali, Mohamed Ramadan, Mahmoud Abouelfetouh, Atef S.A. Abd-Algalil, Eman Salah, and Ahmed H. Khalil. "Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy." Alexandria Journal of Veterinary Sciences 71.2 (2021), 62-69. Print. doi:10.5455/ajvs.134252



APA (American Psychological Association) Style

Sabek, A., Ali, . A., Ramadan, . M., Abouelfetouh, . M., Abd-Algalil, . A. S., Salah, . E. & Khalil, . A. H. (2021) Sedative, Analgesic, Behavioral Effect of Xylazine-Ketamine-Nalbuphine induction Anesthesia in Cats Subjected to Median Celiotomy. Alexandria Journal of Veterinary Sciences, 71 (2), 62-69. doi:10.5455/ajvs.134252





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