E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Research (Original Article) 


Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy.

Abstract
The current study was performed to investigate the comparative effect of Turmeric and vitamin C on the oxidative damage caused by sodium nitrite in rats. Sixty albino rats were used, divided into four equal groups, group (1) considered as a control group, group (2) received sodium nitrite (NaNO2) 30mg/kg.bw., group (3) received (NaNO2) 30mg/kg.bw. and vitamin C 200 mg /kg bw., group (4) received (NaNO2) 30mg/kg.bw. and turmeric 0.5g/ kg.bw. Animals were daily treated for five weeks. Sodium nitrite treated Rats showed a microcytic hypochromic anemia , significant increase (p ≤ 0.05) in total leukocytes (WBCs), total billirubin , lipid peroxidase(LPO), superoxidedismutase (SOD), significant decrease in glutathione reductase (GR), globulin ( β, γ globulin) and vitamin C value as compared to control group. (NaNO2) with Vitamin C treated Rats showed significant increase in RBCs count, HB value, globulin (β, α) and vitamin C value ,significant decrease in total billirubin, (LPO)and (SOD)as compared to (NaNO2) treated group. (NaNO2) with turmeric treated Rats showed slight ameliorating effect through significant increase in RBCs count but hemoglobin value was declined, significant decrease in total billirubin, (LPO)and (SOD), significant increase in globulin ( γ globulin) and (GR) as compared to (NaNO2) treated group. Histopathological changes of sodium nitrite treated rats after five weeks exhibited cytoplasmic vacuolization of hepatocytes, dilated congested veins and mononuclear cells infiltration. The damage also extended to kidney represented by shrinkage glomerular tuft, distention of Bowmans space, degeneration of lining tubular epithelial, The results declared that vitamin C preceded the turmeric in ameliorate the toxic effect of sodium nitrite on rats.

Key words: Sodium nitrite, Turmeric, Vitamin C, Lipid peroxidation, Superoxidedismutase, Glutathione reductase


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Shahenaz M.H. Hassan
Articles by Nahed F. Zaglool
Articles by Sanaa A. El-shamy
on Google
on Google Scholar
Article Statistics
 Viewed: 3398
Downloaded: 604


How to Cite this Article
Pubmed Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. AJVS. 2018; 56(1): 56-68. doi:10.5455/ajvs.278511


Web Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. http://www.alexjvs.com/?mno=278511 [Access: February 08, 2020]. doi:10.5455/ajvs.278511


AMA (American Medical Association) Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. AJVS. 2018; 56(1): 56-68. doi:10.5455/ajvs.278511



Vancouver/ICMJE Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. AJVS. (2018), [cited February 08, 2020]; 56(1): 56-68. doi:10.5455/ajvs.278511



Harvard Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy (2018) Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. AJVS, 56 (1), 56-68. doi:10.5455/ajvs.278511



Turabian Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. 2018. Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. Alexandria Journal of Veterinary Sciences, 56 (1), 56-68. doi:10.5455/ajvs.278511



Chicago Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. "Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats." Alexandria Journal of Veterinary Sciences 56 (2018), 56-68. doi:10.5455/ajvs.278511



MLA (The Modern Language Association) Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy. "Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats." Alexandria Journal of Veterinary Sciences 56.1 (2018), 56-68. Print. doi:10.5455/ajvs.278511



APA (American Psychological Association) Style

Shahenaz M.H. Hassan, Nahed F. Zaglool, Sanaa A. El-shamy (2018) Comparative Studies on Turmeric and Vitamin C on Sodium Nitrite treated Rats. Alexandria Journal of Veterinary Sciences, 56 (1), 56-68. doi:10.5455/ajvs.278511





Most Viewed Articles
  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract & References

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract & References » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Most Downloaded
  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract & References » doi: 10.5455/ajvs.47290

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Most Cited Articles
  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333
    Cited : 8 times [Click to see citing articles]

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232
    Cited : 7 times [Click to see citing articles]

  • Detection of Molecular Characterization of Salmonella enterica isolated from Chicken Meat and Its Products by Using Multiplex PCR
    Heba S. Amin and Abd El-Rahman A. Abd El-Rahman
    AJVS. 2015; 46(1): 155-160
    » Abstract & References » doi: 10.5455/ajvs.196302
    Cited : 5 times [Click to see citing articles]

  • Antifibrotic Effect of Curcumin on Thioacetamide Induced Liver Fibrosis
    Suzan E. Abdou, Nabil M. Taha, Abd El-Wahab A. Mandour, Mohamed A. Lebda, Hanaa R. El Hofi, Amany MSE El-Morshedy
    AJVS. 2015; 45(1): 43-50
    » Abstract & References » doi: 10.5455/ajvs.179458
    Cited : 4 times [Click to see citing articles]

  • Adverse Effects of Ivermectin in comparison with Rafoxanide on Male Rats
    Abd El-Salam F. El-Sawy, Zeynab Kh. El-Maddawy and Soaad A. Seed
    AJVS. 2015; 47(1): 119-128
    » Abstract & References » doi: 10.5455/ajvs.198997
    Cited : 4 times [Click to see citing articles]