E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng .

Adetolase Azizat Bakre, Omolade O Oladele, Oluwaseun O Esan.

Abstract
Garlic (Allium sativum), has proven to be an effective growth promoter and immunostimulant in poultry. It`s ability to enhance cellular immune response was investigated using interferon gamma assay. A total of 100-day-old chicks were divided into 4 groups of 20 each in groups A, B, C and 40 in group D which was further sub-divided into subgroups D1 and D2. Feeds served were supplemented with varying levels of garlic meal i.e. Group A- 0.125%, Group B- 0.25%, Group C -0.5%. Group D- 0% (i.e. D1 and D2). Chicks in all groups were administered Newcastle disease vaccine HB1 strain at day-old, Lasota strain at 3-week-old. At 5-week-old, they were all challenged with the Newcastle Disease Virus Komarov strain except subgroup D2. Twelve chicks were selected randomly from each group (A, B and C as well as subgroup D1), Eight chicks were selected from subgroup D2 and were all bled at 6 week-old, sera were obtained for the assessment of interferon-gamma level and data obtained were subjected to statistical analysis using Analysis of variance and Turkey multiple comparison test (Graph Pad Prism) at p<0.05.
Mean interferon-gamma concentrations showed no significant difference (p>0.05) between groups A (151.160.46 pg/ml), B (151.300.33 pg/ml) and C (152.360.26pg/ml) but these values were significantly higher (p<0.05) than those of subgroups D1 (142.331.9pg/ml) and D2 (127.132.2pg/ml). Also, mean concentration in subgroup D1 was significantly (p<0.05) higher than that of subgroup D2.
The study showed that Garlic has an immunomodulatory effect in commercial chickens via an increased secretion of interferon-gamma, which could be responsible for the reported improvement in vaccinal immune response and its general antibiotic activity.
Key words: Interferon-gamma, Garlic, Cockerels, Cellular Immune Response, Newcastle disease vacci

Key words: Interferon Gamma, Garlic, Cockerels, Cellular Immune Response, Newcastle Disease Vaccines.


 
ARTICLE TOOLS
Abstract
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Adetolase Azizat Bakre
Articles by Omolade O Oladele
Articles by Oluwaseun O Esan
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Bakre AA, Oladele OO, Esan OO, . Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..


Web Style

Bakre AA, Oladele OO, Esan OO, . Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng .. http://www.alexjvs.com/?mno=96795 [Access: August 04, 2020].


AMA (American Medical Association) Style

Bakre AA, Oladele OO, Esan OO, . Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..



Vancouver/ICMJE Style

Bakre AA, Oladele OO, Esan OO, . Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..



Harvard Style

Bakre, A. A., Oladele, O. O., Esan, O. O. & (0) Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..



Turabian Style

Bakre, Adetolase Azizat, Omolade O Oladele, Oluwaseun O Esan, and . 0. Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..



Chicago Style

Bakre, Adetolase Azizat, Omolade O Oladele, Oluwaseun O Esan, and . "Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng .."



MLA (The Modern Language Association) Style

Bakre, Adetolase Azizat, Omolade O Oladele, Oluwaseun O Esan, and . "Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng .."



APA (American Psychological Association) Style

Bakre, A. A., Oladele, O. O., Esan, O. O. & (0) Garlic Enhances Cellular Immune Response Via Increased Secretion of IFN-Gamma in Commercial Chickens. Bakre, A.A1., Oladele, O.A2 and Esan, O2. Avian Diseases Unit, Department of Vet. Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Corresponding author`s email: bakreadetolase@gmail.com, aa.bakre@ui.edu.ng ..





Most Viewed Articles
  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract & References

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract & References » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Most Downloaded
  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract & References » doi: 10.5455/ajvs.47290

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Most Cited Articles
  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333
    Cited : 8 times [Click to see citing articles]

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232
    Cited : 7 times [Click to see citing articles]

  • Detection of Molecular Characterization of Salmonella enterica isolated from Chicken Meat and Its Products by Using Multiplex PCR
    Heba S. Amin and Abd El-Rahman A. Abd El-Rahman
    AJVS. 2015; 46(1): 155-160
    » Abstract & References » doi: 10.5455/ajvs.196302
    Cited : 5 times [Click to see citing articles]

  • Antifibrotic Effect of Curcumin on Thioacetamide Induced Liver Fibrosis
    Suzan E. Abdou, Nabil M. Taha, Abd El-Wahab A. Mandour, Mohamed A. Lebda, Hanaa R. El Hofi, Amany MSE El-Morshedy
    AJVS. 2015; 45(1): 43-50
    » Abstract & References » doi: 10.5455/ajvs.179458
    Cited : 4 times [Click to see citing articles]

  • Adverse Effects of Ivermectin in comparison with Rafoxanide on Male Rats
    Abd El-Salam F. El-Sawy, Zeynab Kh. El-Maddawy and Soaad A. Seed
    AJVS. 2015; 47(1): 119-128
    » Abstract & References » doi: 10.5455/ajvs.198997
    Cited : 4 times [Click to see citing articles]