E-ISSN 2536-9520 | ISSN 1110-2047
 
2026, Vol: 89
89Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 12 Jun 2025
 


The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine

Azza M. Mohamed, Mohamed H. Atwa, Eman R. Abdo, Diana M. Abul Magd.


Abstract
In this work, a trial was conducted to improve sheep reaction of the immune system to the inactivated FMD vaccination by using Zylexis as an immune-modulatory. Three groups of five sheep each were formed from the fifteen sheep. The first group received 2 injections of zylexis (2 ml/sheep, I/M) given on three days interval concurrently with vaccination with one dose of the inactivated FMD (SAT-2) vaccine (1ml/sheep, S/C); the second group got the vaccination and nothing else, while the third group served as a control and did not get any inoculation at all. To evaluate the humeral immune response, SNT and ELISA were used to serum samples, and blood samples obtained while taking heparin as an anticoagulant to assess the cellular immune response. Over the course of 40 weeks after vaccination, the findings showed that sheep given the inactivated zylexis vaccine had a stronger cellular and humoral immune response than sheep given the inactivated FMD (SAT-2) vaccine alone. In order to prolong the duration of immunity, it might be suggested to combine it with FMD vaccination. This would boost the immunological response of vaccinated animals.

Key words: FMD, SAT-2, Zylexis, SNT, ELISA,


 
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How to Cite this Article
Pubmed Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS. 2025; 86(0): 130-135. doi:10.5455/ajvs.259075

Web Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. https://www.alexjvs.com/?mno=259075 [Access: June 27, 2026]. doi:10.5455/ajvs.259075

AMA (American Medical Association) Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS. 2025; 86(0): 130-135. doi:10.5455/ajvs.259075


Vancouver/ICMJE Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS. (2025), [cited June 27, 2026]; 86(0): 130-135. doi:10.5455/ajvs.259075


Harvard Style

Mohamed, A. M., Atwa, . M. H., Abdo, . E. R. & Magd, . D. M. A. (2025) The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS, 86 (0), 130-135. doi:10.5455/ajvs.259075


Turabian Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. 2025. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. Alexandria Journal of Veterinary Sciences, 86 (0), 130-135. doi:10.5455/ajvs.259075


Chicago Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. "The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine." Alexandria Journal of Veterinary Sciences 86 (2025), 130-135. doi:10.5455/ajvs.259075


MLA (The Modern Language Association) Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. "The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine." Alexandria Journal of Veterinary Sciences 86.0 (2025), 130-135. Print. doi:10.5455/ajvs.259075


APA (American Psychological Association) Style

Mohamed, A. M., Atwa, . M. H., Abdo, . E. R. & Magd, . D. M. A. (2025) The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. Alexandria Journal of Veterinary Sciences, 86 (0), 130-135. doi:10.5455/ajvs.259075




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    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110-204 ... Read more.



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    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

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