Ameliorative Effect of  N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers

Ashraf Elkomy; Soad S. Belih; Faten Elsayed; Elrefaey Aboelftouh; Hawary S. Ibrahiem

doi:10.5455/ajvs.146912

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Original Article

AJVS. 2023; 77(2): 42-46

doi: 10.5455/ajvs.146912

Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers

Ashraf Elkomy, Soad S. Belih, Faten Elsayed, Elrefaey Aboelftouh, Hawary S. Ibrahiem.

Abstract
Abstract
This study was designed to evaluate the Ameliorative effect of N-acetylcysteine (NAC) against possible florfenicol (FFC)-induced intestinal injuries in broiler chicks. A total of 120 broiler chicks were allocated into 4 equal groups. Group (1) was kept as a control, while group (2) administered with NAC (100 mg ̸ L of drinking water for 5 days from 15 to 20 days of age. Group (3) was administered with toxic dose of FFC (60mg ̸ kg B.Wt.) orally for 5 days from 18 to 22 days of age. Group (4) was co-administered with NAC with FFC with the same previous doses on the same treatment periods. The histopathological examination was performed to evaluate NAC-ameliorative effects. Results ensure that FFC induced intestinal injuries in broilers and NAC can ameliorate such deleterious effects which reflected by an enhancement histopathological findings.

Key words: Florfenicol, N-acetylcysteine, intestines and broiler chicks

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Pubmed Style

Elkomy A, Belih SS, Elsayed F, Aboelftouh E, Ibrahiem HS. Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. AJVS. 2023; 77(2): 42-46. doi:10.5455/ajvs.146912

Web Style

Elkomy A, Belih SS, Elsayed F, Aboelftouh E, Ibrahiem HS. Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. https://www.alexjvs.com/?mno=146912 [Access: May 05, 2025]. doi:10.5455/ajvs.146912

AMA (American Medical Association) Style

Elkomy A, Belih SS, Elsayed F, Aboelftouh E, Ibrahiem HS. Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. AJVS. 2023; 77(2): 42-46. doi:10.5455/ajvs.146912

Vancouver/ICMJE Style

Elkomy A, Belih SS, Elsayed F, Aboelftouh E, Ibrahiem HS. Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. AJVS. (2023), [cited May 05, 2025]; 77(2): 42-46. doi:10.5455/ajvs.146912

Harvard Style

Elkomy, A., Belih, . S. S., Elsayed, . F., Aboelftouh, . E. & Ibrahiem, . H. S. (2023) Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. AJVS, 77 (2), 42-46. doi:10.5455/ajvs.146912

Turabian Style

Elkomy, Ashraf, Soad S. Belih, Faten Elsayed, Elrefaey Aboelftouh, and Hawary S. Ibrahiem. 2023. Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers. Alexandria Journal of Veterinary Sciences, 77 (2), 42-46. doi:10.5455/ajvs.146912

Chicago Style

Elkomy, Ashraf, Soad S. Belih, Faten Elsayed, Elrefaey Aboelftouh, and Hawary S. Ibrahiem. "Ameliorative Effect of N-acetylcysteine against Florofenicol-induced Intestinal Injuries in Broilers." Alexandria Journal of Veterinary Sciences 77 (2023), 42-46. doi:10.5455/ajvs.146912

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