Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.

Mohamed S. Helal; Fatma M. Youssef; Mohamed K. Moursi; Waleed F. Khalil; Mohamed M. Abdel-Daim

doi:10.5455/ajvs.179869

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Original Article
Online Published: 15 Apr 2015

AJVS. 2015; 45(1): 13-25

doi: 10.5455/ajvs.179869

Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.

Mohamed S. Helal, Fatma M. Youssef, Mohamed K. Moursi, Waleed F. Khalil, Mohamed M. Abdel-daim.

Abstract
This study was designed to compare the effect of the prebiotic and antimicrobial growth promoter (AGP) on the growth performance, blood constituent, intestinal bacteriology and histomorphometric parameters as well as humeral immunity of broiler chicks. A total of 90 unsexed commercial Cobb chicks were randomly assigned to 3 dietary treatments (control, AGP and prebiotic groups), each group contain 30 chicks. Each group subdivided into 3 replicates, 10 chicks each, and was reared for 42 days. The prebiotic supplemented group showed a significant improvement in growth performance parameters than the control and AGP-supplemented groups. Total leukcocytic count, lymphocyte percent, total protein, total globulin and gamma globulin were significantly increased in the broilers fed on prebiotics. Moreover, prebiotics supplementation significantly reduced heterophil percent, heterophil/ lymphocyte ratio (H/L ratio), albumin/globulin ratio, aspartate and alanine aminotransferase (AST and ALT), uric acid and creatinine compared to the AGP-supplemented group and control group. The AGP-supplemented group exhibited a significant reduction in the total aerobic count than the control and prebiotic-supplemented groups. However, the prebiotic supplemented group showed a significant reduction in the coliform count than the control and antibiotic supplemented groups. The prebiotic supplemented group induced a significant increase in the villus height (VH) all over the small intestine. In addition, it induced a significant increase in villus height: crypt depth ratio in the duodenum and jejunum than the control and antibiotic supplemented groups. However, there were no significant differences among the different groups regard to the crypt depth (CD) in the duodenum and jejunum. Prebiotics could be considered as safe and effective antimicrobial alternatives for broiler chicks growth performance, immunity and intestinal bacteriology and morphology.

Key words: prebiotic; chlortetracycline; growth; hematology; biochemistry; intestine; immunity

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How to Cite this Article

Pubmed Style

Helal MS, Youssef FM, Moursi MK, Khalil WF, Abdel-daim MM. Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. AJVS. 2015; 45(1): 13-25. doi:10.5455/ajvs.179869

Web Style

Helal MS, Youssef FM, Moursi MK, Khalil WF, Abdel-daim MM. Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. https://www.alexjvs.com/?mno=179869 [Access: May 04, 2025]. doi:10.5455/ajvs.179869

AMA (American Medical Association) Style

Helal MS, Youssef FM, Moursi MK, Khalil WF, Abdel-daim MM. Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. AJVS. 2015; 45(1): 13-25. doi:10.5455/ajvs.179869

Vancouver/ICMJE Style

Helal MS, Youssef FM, Moursi MK, Khalil WF, Abdel-daim MM. Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. AJVS. (2015), [cited May 04, 2025]; 45(1): 13-25. doi:10.5455/ajvs.179869

Harvard Style

Helal, M. S., Youssef, . F. M., Moursi, . M. K., Khalil, . W. F. & Abdel-daim, . M. M. (2015) Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. AJVS, 45 (1), 13-25. doi:10.5455/ajvs.179869

Turabian Style

Helal, Mohamed S., Fatma M. Youssef, Mohamed K. Moursi, Waleed F. Khalil, and Mohamed M. Abdel-daim. 2015. Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.. Alexandria Journal of Veterinary Sciences, 45 (1), 13-25. doi:10.5455/ajvs.179869

Chicago Style

Helal, Mohamed S., Fatma M. Youssef, Mohamed K. Moursi, Waleed F. Khalil, and Mohamed M. Abdel-daim. "Effectiveness of prebiotic as an alternative to the antimicrobial growth promoter on growth performance, blood constituents, intestinal healthiness and immunity of broilers.." Alexandria Journal of Veterinary Sciences 45 (2015), 13-25. doi:10.5455/ajvs.179869

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APA (American Psychological Association) Style

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