Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model

Salma Gomaa; Hoda Elkhenany; Howaida Abu-Ahmed; Hosam Gafaar; Ramadan Abdelwahed

doi:10.5455/ajvs.182328

2025, Vol: 86

86Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Original Article

AJVS. 2024; 80(0): 164-171

doi: 10.5455/ajvs.182328

Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model

Salma Gomaa, Hoda Elkhenany, Howaida Abu-ahmed, Hosam Gafaar, Ramadan Abdelwahed.

Abstract
In this study, gelatin (GE) will be used as a carrier to enhance platelet-rich plasma's (PRP) effects on the wound-healing process. PRP/GE was created by conjugating 20% GE with freshly prepared autologous PRP. Following rabbits with experimentally generated full-thickness skin wounds, the ability of the skin to regenerate was evaluated. Evaluation considered the macroscopic features of wounds, wound healing rate % and histologic findings for specimens collected after 3, 10 and 21 days. The PRP/GE treated wounds revealed noticeably improved and better closure. This improvement may be attributable to the advantages of combining PRP with GE as a bioactive substance that may regulate the release of growth factors and support angiogenesis. It might be concluded that PRP/GE has the ability to quicken the healing process. The therapeutic impact of PRP was boosted by the GE carrier. According to these data, PRP/GE may be suggested as a viable therapy for wound healing.

Key words: PRP, gelatin, wound healing, full-thickness wounds, bioactive material, skin regeneration, growth factors

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Salma Gomaa Articles by Hoda Elkhenany Articles by Howaida Abu-Ahmed Articles by Hosam Gafaar Articles by Ramadan Abdelwahed
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Gomaa S, Elkhenany H, Abu-ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. 2024; 80(0): 164-171. doi:10.5455/ajvs.182328

Web Style

Gomaa S, Elkhenany H, Abu-ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. https://www.alexjvs.com/?mno=182328 [Access: May 05, 2025]. doi:10.5455/ajvs.182328

AMA (American Medical Association) Style

Gomaa S, Elkhenany H, Abu-ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. 2024; 80(0): 164-171. doi:10.5455/ajvs.182328

Vancouver/ICMJE Style

Gomaa S, Elkhenany H, Abu-ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. (2024), [cited May 05, 2025]; 80(0): 164-171. doi:10.5455/ajvs.182328

Harvard Style

Gomaa, S., Elkhenany, . H., Abu-ahmed, . H., Gafaar, . H. & Abdelwahed, . R. (2024) Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS, 80 (0), 164-171. doi:10.5455/ajvs.182328

Turabian Style

Gomaa, Salma, Hoda Elkhenany, Howaida Abu-ahmed, Hosam Gafaar, and Ramadan Abdelwahed. 2024. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. Alexandria Journal of Veterinary Sciences, 80 (0), 164-171. doi:10.5455/ajvs.182328

Chicago Style

Gomaa, Salma, Hoda Elkhenany, Howaida Abu-ahmed, Hosam Gafaar, and Ramadan Abdelwahed. "Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model." Alexandria Journal of Veterinary Sciences 80 (2024), 164-171. doi:10.5455/ajvs.182328

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Gomaa, S., Elkhenany, . H., Abu-ahmed, . H., Gafaar, . H. & Abdelwahed, . R. (2024) Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. Alexandria Journal of Veterinary Sciences, 80 (0), 164-171. doi:10.5455/ajvs.182328

About Alexandria Journal of Veterinary Sciences

Contact Information

How to cite this article