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Original Article 


Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade.

Cited by (2)

Abstract
Pentavalent vanadium (metavanadate salt) toxicity is a challenging environmental hazard that affects living organisms. Studies have shown that plants play important roles in protecting against heavy metal toxicity. This study was designed to evaluate the protective activity of ethanolic extracts of Grewia carpinifolia leaves following vanadium toxicity.
Twenty five male Swiss mice were randomly divided into five groups (A–E) of five rats each. Group A rats served as control and were given distilled water, Group B was administered with sodium metavanadate and a known antioxidant agent; α-tocopherol, Groups C and D were administered with sodium metavanadate and ethanolic extract of Grewia carpinifolia leaves orally at 100 and 200 mg/kg body weight respectively while Group E was administered with only sodium metavanadate.
After a daily single oral dosing for seven days, changes in haematology and serum biochemistry parameters were analysed. Sodium metavanadate caused a significant decrease (p≤0.05) in haematocrit levels, haemoglobin (Hb) concentration, white blood cell count, neutrophil count and serum cholesterol level. A significant (p≤0.05) lymphocytosis was also observed in the group administered with sodium metavanadate alone. G. carpinifolia extract given concomitantly with sodium metavanadate was able to restore PCV, Hb concentrations and serum total protein to levels comparable with the control and standard groups. Grewia carpinifolia also significantly reduced the elevated serum levels of AST and ALT after vanadium induced hepatotoxicity. Our findings suggest that G. carpinifolia extract protected against the toxicity induced by vanadium; the plant extract at 200 mg/kg however appear to offer a better protection.

Key words: vanadium, Grewia carpinifolia, haematology, serum biochemistry, Swiss mice


 
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REFERENCES
Adedapo, A.A., Abatan, M.O., Olorunsogo, O.O. 2004. Toxic effects of some plants in the genus Euphorbia on haematological and biochemical parameters of rats. Vet. Arch. 74(1): 53-62.
Adedara I.A., Teberen R., Ebokaiwe A.P., Ehwerhemuepha T. and Farombi E.O., 2011. Induction of oxidative stress in liver and kidney of rats exposed to Nigerian bonny light crude oil. Environ Toxicol. 27 (6): 372–379. [DOI via Crossref]    [Pubmed]   
AfesehNgwa,  H.,  Kanthasamy,  A.,  Anantharam,  V.,  Song  C.,  Witte,  T.,  Houk, R., Kanthasamy, A.G. 2009. Vanadium induces dopaminergic neurotoxicity via protein kinase C-delta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease. Toxicol. Appl. Pharmacol. 240: 273–285. [Pubmed]    [PMC Free Fulltext]   
Aglal, A.A. 2010. Histological and Physiological alterations resulted from aqueous extract of Grewia tenax administration in Swiss albino mice. SCVMJ. 15(1):189-197.
Ahamed, B.K., Krishna, V., Gowdru, H.B., Rajanaika, H., Kumaraswamany, H.M., Rajshekarappa, S., Dandin, C.J., Mahaderan, K.M. 2007. Isolation of bactericidal constituent from the stem bark extract of Grewia tilaefoliaVahl. Res. J. Med. Plant 1(3):72-82. [DOI via Crossref]   
Ahsan, M.R., Islam, K.M., Bulbul, I.J. 2009. Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride-induced hepatotoxicity in rats.Europ. J. Scientific Res. 37(2):302-310.
Ajayi, I.A., Ajibade, O., Oderinde, R.A. 2011. Preliminary Phytochemical Analysis of some Plant Seeds. Res. J. Chem. Sci. 1(3):58-62.
Altamirano-Lozano, M.A., Alvarez-Barrera, L., Mateos-Nava, R.A., Fortoul, T.I., Rodriguez-Mercado, J.J. 2014. Potential for genotoxic and reprotoxic effects of vanadium compounds due to occupational and environmental exposures. J. Immunotoxicol.11(1): 19-27. [DOI via Crossref]    [Pubmed]   
AOAC Association of Official Analytical Chemists 1970. Official methods of Analysis: 11th Ed. Washington D.C.
Aqil, F., Ahmed, I., Mehmood, Z. 2006. Antioxidants and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turk. J. Biol. 30:177–183.
AragĂłn, A.M., Altamirano-Lozano, M. 2001. Sperm and testicular modifications induced by subchronic treatments with vanadium (V) in CD-1 mice. ReprodToxicol. 15:145–151. [DOI via Crossref]   
Aureliano, M., Gândara, R.M. 2005. Decavanadate effects in biological systems. J Inorg. Biochem. 99:979–985. [DOI via Crossref]    [Pubmed]   
Barvitenko, N.N., Adragna, N.C., Weber, R.E. 2005. Erythrocyte signal transduction pathways, their oxygenation dependence and functional significance. Cell Physiol. Biochem. 15:1-18. [DOI via Crossref]    [Pubmed]   
Bhumi, G., Savithramma, N. 2014. Screening of pivotal medicinal plants for qualitative and quantitative phytochemical constituents Int. J. Pharm.Pharmaceut. Sci. 6(3):63-65.
Bracci, R., Perrone, S., Buonocore, G. 2002.Oxidant injury in neonatal erythrocytes during the perinatal period.Acta Paediatr Suppl. 91:130-134. [DOI via Crossref]    [Pubmed]   
Chang, S. 2009. Liver Enzymes (online). Available from URL: http://www. Liver Enzymes on RightHealth.html
Coles, E.H. 1986. Veterinary Clinical Pathology 4th ed. Saunders Company Philadelphia. pp. 126-127.
Cooper, R.G. 2007.Vanadium pentoxide inhalation. Indian J.Occupat. Environ. Med.11(3):97-102. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
Crawford, J., Dale, D.C., Lyman, G.H. 2004. Chemotherapy-induced neutropenia: Risks, consequences and new directions for its management. Cancer 100:228–237. [DOI via Crossref]    [Pubmed]   
Cuesta, S., FrancĂ©s, D., GarcĂ­a, G.B. 2011. ROS formation and antioxidant status in brain areas of rats exposed to sodium metavanadate. Neurotoxicol. Teratol. 3: 1–6. [DOI via Crossref]   
Dai, S., McNeill, J. H. 1994. One-year treatment of non-diabetic and streptozotocin-diabetic rats with vanadyl sulphate did not alter blood pressure or haematological indices. Pharmacol. Toxicol. 74 (2):110–115. [DOI via Crossref]    [Pubmed]   
Dailiah, R.P., Padmalatha, C. 2012. Effect of herbal preparation on heavy metal (cadmium) induced antioxidant system in female Wistar rats. J. Med. Toxicol. 8(2):101-107. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
Elshaari, F.A., Hadad, G., Barassi, I.F. 2011.Effect of Sodium Vanadate on Liver Function of Experimental Rats. J. Basic Med. Allied Sci. 1: 5-10.
Erdmann, E., Werdan, K., Krawietz, W., Schmitz, W., Scholz, H. 1984 Vanadate and its significance in biochemistry and pharmacology. Bioch. Pharmacol. 33: 945-950. [DOI via Crossref]   
Fatum, A., El-Shaari, S., Syed, S.H., Mustafa, M.E., Kilani, M.G. 2002. Does ascorbic acid protect against vanadium neurotoxicity in different regions of rat brain? Neurosciences 7(4):278-286.
Fawcett, J. P., Farquhar, S. J., Thou, T., Shand, B. I. 1997. Oral vanadylsulphate does not affect blood cells, viscosity or biochemistry in humans. Pharmacol. and Toxicol. 80(4): 202–206. [DOI via Crossref]    [Pubmed]   
Federal Government of Nigeria. 1991. Niger-Delta Regional Development Master Plan: Niger Delta Region Land and People pg 49.
Föller, M., Sopjani, M., Mahmud, H., Lang, F. 2008.Vanadate-induced suicidal erythrocyte death. Kidney and Blood Pressure Res.31:87–93. [DOI via Crossref]    [Pubmed]   
Galli, A., Vellosi, R., Fiorio, R., Groce, C., DelCarratore, R., Morichetti, E., Giromeni, L., Rosellini, D., Bronzetti, G. 1991. Genoticixity of vanadium compounds in yeast and cultured mammalian cells. Teratogen, Carcinogen. Mutagen. 11:175-183. [DOI via Crossref]   
Garcia, G.B., Sturtz, N., Martinez, A.I., Biancardi, M.E. 2004.Morphological Alterations of Central Nervous System (CNS) Myelin in Vanadium (V)-Exposed Adult Rats. Drug and Chemical Toxicol. 27(3): 281-293. [DOI via Crossref]    [Pubmed]   
Gebauer, J., Patzelt, A., Hammer, K., Buerkert, A. 2007. First record of Grewia tenax (Forssk.)Fiori in northern Oman, a valuable fruit producing shrub. Genetic Resources and Crop Evolut. 54:1153-1158. [DOI via Crossref]   
Goyal, P.K. 2012. Phytochemical and pharmacological properties of the genus Grewia: A Review. International J. Pharm. and Pharmaceut. Sci. 4(4):72-78.
Habib, H.M., Ibrahim, W.H.2011. Nutritional quality of 18 date fruit varieties. Int. J. Food Sci. Nutr. 62:544–51. [DOI via Crossref]    [Pubmed]   
Haider, S.S., El-Fakhri, M. 1991.Action of alpha tocopherol on vanadium-stimulated lipid peroxidation in rat brain.Neurotoxicology 12:79-89. [Pubmed]   
Haider, S.S., Abel-gayoum, A., el-Fakhri, M., Ghwarsha, K.M. 1998.Effect of Selenium on Vanadium Toxicity in Different Regions of Rat Brain. Hum. Exp. Toxicol. 17(1):23-28. [DOI via Crossref]    [Pubmed]   
Hoda, E.A., Farid, M.M., Abozid, K.E. 2012.Short term effects of vanadium and nickel intoxication on rats' liver antioxidant defense system. International Journal of Academic Research 4(5):23-28. [DOI via Crossref]   
Hosseini, M., Seyedrazi, N., Shahraki, J., Pourahmad, J. 2012. Vanadium induces liver toxicity through reductive activation by glutathione and mitochondrial dysfunction. Advances in Biosci. Biotechnol. 3:1096-1103. [DOI via Crossref]   
Huang, C., Kuo, E. 2007. Mechanism of hypokalemia in magnesium deficiency. Journal of the American Society of Nephrology 18(10):2649-52. [DOI via Crossref]    [Pubmed]   
Kind, P.R., King, E. 1954.Estimation of plsma phosphatase by determination of hydrolysed phenol with amino antipyrine.J Clin. Pathol.7:322. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
Kordowiak, A. M., Holko, P. 2009. Pochodnewanadujakozwiązki o. istotnym znaczeniu biologicznym. Część I. Działanie przeciwcukrzy- cowe. Post BiolKom 36:361–376 (in Polish)
Magda, E.A., Hala, B.B., Haydar, E.B., Ahmed, A.A. 2012. Effects of Grewia tenax (Guddaim) as a natural food on the hemoglobin level and growth among displaced children of Darfur State, Western Sudan. Journal of Med. and Med. Sci. 3(11):729-733.
Mallay, H.T., Evelyn, K.A. 1937. Estimation of serum bilirubin level with the photoelectric colorimeter. J Biological Chem. 119:481-484.
Manju, P., Vivek, K.,Jaya, P.Y. 2011.In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases.Annals of Clinical Microbiology and Antimicrobials10:21-25. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
MarkkuKiviluoto, M.D., LauriPyy, M.S., ArtoPakarinen, M.D. 1981. Clinical Laboratory results of Vanadium-Exposed Workers. Arch. Environm. Health 36(3):109-113. [DOI via Crossref]    [Pubmed]   
Meiathnin, F., Bardelli, F., Giamini, G., Tarli, P. 1978. The 4-Hydroxybenzoate-4-aminophenazone chromogenic system used in the enzymic determination of serum cholesterol.Clin. Chem. 24:2161-2165.
Murugaian, P., Ramamurthy, V., Karmegam, N. 2008. Hepatoprotective Activity of Wedeliacalendulacea L. against Acute Hepatotoxicity in rats. Res. J. Agriculture Biol. Sci. 4(6):685-87.
Narayanaswamy, N., Balakrishna, K.P. 2011.Evaluation of some Medicinal Plants for their Antioxidant Properties. Int. J. Pharm. Tech. Res. 3(1):381-385.
NIEHS National Institute of Environmental Health Sciences 2008. Chemical Information Review Document for Oral Exposure to Tetravalent and Pentavalent Vanadium Compounds Department of Health and Human Services Res. Triangle Park, NC pg 5.
Obianime,A.W., Gogo-Abite, M., Roberts, I.I. 2009. The effects of ammonium metavanadate on biochemical hormonal, haematological and histopathological parameters of the female Wistar rats Nigerian J. Physiol. Sci. 24(2):187-194. [Pubmed]   
Ola-Davies, F.O., Adebiyi, O.E., Ewete, A. 2013. Modulatory effects of ethanol extract of Spondiasmombin leaves on sodium arsenite induced toxicity. Trop. Vet. 31(1):30-40.
Olopade, J.O., Connor, J.R. 2011. Vanadium and Neurotoxicity: A Review. Current Topics in Toxicol.7:33-39
Olopade, J.O, Fatola, I.O., Olopade, F.E, 2011. Vertical Administration of Vanadium through Lactation Induces Behavioural and Neuromorphological Changes: Protective Role of Vitamin E. Nig. J. Physiol. Sci. 26:55-60. [Pubmed]   
Olorunnisola, O.S., Bradley, G., Afolayan, A.J. 2011. Antioxidant properties and cytotoxicity evaluation of methanolic extract of dried and fresh rhizomes of Tulbaghiaviolacea. Afr. J. Pharmacy Pharmacol. 5:2490–2497. [DOI via Crossref]   
Reitman, S., Frankel, S.A. 1957. Colorimetric method for the determination of serum glutamicOxaloacetic and glutamic pyruvic transaminase. Am. J. Clin. Pathol. 28:56-63. [Pubmed]   
Sharma, S.K., Lalit, S., Suruchi, S. 2013. A Review On Medicinal Plants Having Antioxidant Potential. Indian J. Res. Pharmacy Biotechnol. 1(3): 404-409.
Shi, X., Jiang, H., Mao, Y., Ye, J., Sayotti, U. 1996.Vanadium(V)-mediated free radical generation and related 2-deoxyguanosine hydroxylation and DNA damage. Toxicol. 106:27-38. [DOI via Crossref]   
Sidhu, P., Garg, M.L., Dhawan, D.K. 2004. Protective role of zinc in nickel induced hepatotoxicity in rats. Chem. Biol. Interact. 150:199-209. [DOI via Crossref]    [Pubmed]   
Soares, S.S., Martins, H., GutiĂ©rrez-Merino, C., Aureliano, M. 2008. Vanadium and cadmium in vivo effects in teleost cardiac muscle: Metal accumulation and oxidative stress markers. Pharmacology, Toxicology & Endocrinol. 147:168-178. [DOI via Crossref]   
Venkataraman, B.V., Sudha, S. 2005. Vanadium Toxicity. Asian J. Exp. Sci. 19(2):127-134.
Yang, X., Wang, K., Lu, J., Crans, D. C. 2003. Membrane transport of vanadium compounds and the interaction with the erythrocyte membrane coordination. Chemistry Rev. 237 (1-2): 103–111,
Yang, X.G., Yang, X.D., Yuan, L., Wang, K. Crans, D.C. 2004.The permeability and cytotoxicity of insulinmimetic vanadium compounds. Pharmaceut. Res. 2:1026-1033. [DOI via Crossref]   
Yeh, S.C., Leveille, G. A. 1973.Significance of skin as a site of fatty acid and cholesterol synthesis in the chick. Proc. Soc. Exp. Biol. Med. 142:115-119. [DOI via Crossref]    [Pubmed]   
Zaporowska, H., SĹ‚otwiĹ„ska, M. 1996. Effect of vanadium on rat erythrocytes in vitro. Folia Histochemicaet Cytobiologica 34(1): 99–100. [Pubmed]   
Zaporowska, H., Wasilewski, W. 1992. Haematological results of vanadium intoxication in Wistar rats. Comparative Biochemistry and Physiology 101(1):57–61. [DOI via Crossref]   
Zychlinski, L., Byczkowski, J.Z. 1990. Inhibitory effects of vanadium pentoxide on respiration of rat liver mitochondria Archives of Environ. Contamination Toxicol. 19 (1): 138-142. [DOI via Crossref]   

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How to Cite this Article
Pubmed Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. 2015; 47(1): 24-31. doi:10.5455/ajvs.189645


Web Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. http://www.alexjvs.com/?mno=189645 [Access: November 27, 2020]. doi:10.5455/ajvs.189645


AMA (American Medical Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. 2015; 47(1): 24-31. doi:10.5455/ajvs.189645



Vancouver/ICMJE Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS. (2015), [cited November 27, 2020]; 47(1): 24-31. doi:10.5455/ajvs.189645



Harvard Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade (2015) Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. AJVS, 47 (1), 24-31. doi:10.5455/ajvs.189645



Turabian Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. 2015. Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. Alexandria Journal of Veterinary Sciences, 47 (1), 24-31. doi:10.5455/ajvs.189645



Chicago Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. "Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity." Alexandria Journal of Veterinary Sciences 47 (2015), 24-31. doi:10.5455/ajvs.189645



MLA (The Modern Language Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade. "Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity." Alexandria Journal of Veterinary Sciences 47.1 (2015), 24-31. Print. doi:10.5455/ajvs.189645



APA (American Psychological Association) Style

Olamide E. Adebiyi, Ayobami D. Obisesan,Funsho O. Olayemi, James O. Olopade (2015) Protective effect of ethanolic extract of Grewia carpinifolia leaves on vanadium induced toxicity. Alexandria Journal of Veterinary Sciences, 47 (1), 24-31. doi:10.5455/ajvs.189645





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