E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 85
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Original Article
Online Published: 19 Apr 2025
 


Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos

Arwa Adress Ahmed.


Abstract
Many women nowadays suffer from muscle cramps, and this also occurs during pregnancy, Pregnant women may have to take medication to relieve this pain. One of these treatments is cyclobenzaprine. The current study was conducted on pregnant female mice by giving them an aqueous solution of the drug from the first day of pregnancy. The mice were divided into three groups, the first was the control group, the second was explained in (D11), and the third was explained in (D17). The results showed that the treatment had a large number of effects, including the death of a large number of fetuses, the phenotypic changes that occurred in the uterine horns, and the phenotypic deformities that appeared in the fetuses on the two days of the experiment, including Hemorrhage, Myoma, Physocephalic, Absence of Eye, Macrohinia. And a number of pathological tissue changes, including focal infiltration of mononuclear inflammatory cells in the sub-mucosal layer, neutrophilic infiltrates The study concluded that this treatment causes many side effects and that pregnant women should be careful when taking it or any type of medication during pregnancy.

Key words: Cyclobenzaprine, Embryos, Histopathological, Stomach


 
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Pubmed Style

Arwa Adress Ahmed|. Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. AJVS. Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242

Web Style

Arwa Adress Ahmed|. Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. https://www.alexjvs.com/?mno=250242 [Access: April 20, 2025]. doi:10.5455/ajvs.250242

AMA (American Medical Association) Style

Arwa Adress Ahmed|. Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. AJVS. Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242


Vancouver/ICMJE Style

Arwa Adress Ahmed|. Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. AJVS, [cited April 20, 2025]; Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242


Harvard Style

Arwa Adress Ahmed| (0) Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. AJVS, Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242


Turabian Style

Arwa Adress Ahmed|. 0. Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. Alexandria Journal of Veterinary Sciences, Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242


Chicago Style

Arwa Adress Ahmed|. "Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos." Alexandria Journal of Veterinary Sciences Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242


MLA (The Modern Language Association) Style

Arwa Adress Ahmed|. "Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos." Alexandria Journal of Veterinary Sciences Online First: 19 Apr, 2025. Web. 20 Apr 2025 doi:10.5455/ajvs.250242


APA (American Psychological Association) Style

Arwa Adress Ahmed| (0) Effect of Cyclobenzaprine Drug on the morphological characteristics of different Embryonic developmental stages in pregnant mice Mus musculus embryos. Alexandria Journal of Veterinary Sciences, Online First: 19 Apr, 2025. doi:10.5455/ajvs.250242




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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