E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 85
85Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article 


Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats

Enas Abd El-aziz Tahoun, Rasha Salah Mohammed, Gehad Rashad Donia.


Abstract
Abstract
This study aimed to evaluate the effect of green tea extract (GTE) and vitamin C as antioxidants on the biochemical oxidative stress parameters and histopathological changes induced by fenitrothion pesticide in liver and kidney of albino rats. Twenty-four rats were divided into four groups; group one (control), group two received 10 mg/kg b.wt. of FNT orally, group three received FNT daily plus green tea extract at a concentration of 3% w/v and group four received FNT daily plus vitamin C at a concentration of 2 g ascorbic acid/l water. The experiment was conducted for six weeks. Blood samples were taken for biochemical parameters, but the histopathological studies were carried out on liver and kidney tissues at the end of the experiment. Damage in the tissue samples was observed and confirmed with elevation of oxidative stress marker (MDA). Exposure of rats to fenitrothion induced significant increase of MDA and decrease in the values of SOD, GSH, CAT, TAC compared to control one in both serum and tissues samples. However, administration of green tea and vitamin C to FNT treated group decreased in the values of MDA and improved the values of SOD,GSH and CAT toward the control values in both serum and tissues but could not normalize it. Total antioxidant capacity (TAC) level showed a significant increase with FNT plus vitamin C and the FNT plus GTE treated groups compared to the FNT group. Green tea and vitamin C, probably due to their strong antioxidant properties could improve and partially counteracts the toxic effect of FNT on oxidative stress parameters and repair the destructive effects of its damage in rat's liver and kidney tissues especially with GTE treated groups.

Key words: Key words: Fenitrothion, toxicity, green tea, vitamin C, histopathology, antioxidant enzymes, rats.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Enas Abd El-Aziz Tahoun
Articles by Rasha Salah Mohammed
Articles by Gehad Rashad Donia
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Tahoun EAE, Mohammed RS, Donia GR. Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. AJVS. 2018; 57(1): 74-86. doi:10.5455/ajvs.296219

Web Style

Tahoun EAE, Mohammed RS, Donia GR. Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. https://www.alexjvs.com/?mno=296219 [Access: March 27, 2025]. doi:10.5455/ajvs.296219

AMA (American Medical Association) Style

Tahoun EAE, Mohammed RS, Donia GR. Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. AJVS. 2018; 57(1): 74-86. doi:10.5455/ajvs.296219


Vancouver/ICMJE Style

Tahoun EAE, Mohammed RS, Donia GR. Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. AJVS. (2018), [cited March 27, 2025]; 57(1): 74-86. doi:10.5455/ajvs.296219


Harvard Style

Tahoun, E. A. E., Mohammed, . R. S. & Donia, . G. R. (2018) Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. AJVS, 57 (1), 74-86. doi:10.5455/ajvs.296219


Turabian Style

Tahoun, Enas Abd El-aziz, Rasha Salah Mohammed, and Gehad Rashad Donia. 2018. Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. Alexandria Journal of Veterinary Sciences, 57 (1), 74-86. doi:10.5455/ajvs.296219


Chicago Style

Tahoun, Enas Abd El-aziz, Rasha Salah Mohammed, and Gehad Rashad Donia. "Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats." Alexandria Journal of Veterinary Sciences 57 (2018), 74-86. doi:10.5455/ajvs.296219


MLA (The Modern Language Association) Style

Tahoun, Enas Abd El-aziz, Rasha Salah Mohammed, and Gehad Rashad Donia. "Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats." Alexandria Journal of Veterinary Sciences 57.1 (2018), 74-86. Print. doi:10.5455/ajvs.296219


APA (American Psychological Association) Style

Tahoun, E. A. E., Mohammed, . R. S. & Donia, . G. R. (2018) Histopathological and Biochemical Studies on The Effect of Green Tea Extract and vitamin C Against Fenitrothion Toxicity in Male Albino Rats. Alexandria Journal of Veterinary Sciences, 57 (1), 74-86. doi:10.5455/ajvs.296219




Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

    •
    Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

    •
    Most Cited Articles
    Most Cited Articles

    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

    email: ajvs@alexu.edu.eg
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use