E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies

El-Awad M. El Hassan, Omar A. Al-Jabr, Sabry M. El-Bahr.

Abstract
TThe aim of this study is to determine the pattern of immune response during Trypanosoma evansi infection as a preliminary step for production of high affinity antibodies for use in immunoassays. Antibody response to Typanosoma evansi infection in mice was monitored during a short and a long immunization protocols. Both protocols yielded immunoglobulin M (IgM) and immunoglobulin G (IgG) responses. Observed initial antibody response was of an IgM type and later replaced by an IgG response. The IgM response was similar in both immunization protocols. It first detected on day 4, reached a peak level on day 6 and declined thereafter until it disappeared on day 37-post infection. The IgG response in the short protocol was first detected on day 17-post infection, reached a peak level on day 23 and maintained a high level up to the end of the experiment on day 45 post-infection. The IgG response in the long protocol was first detected on day 10-post infection, reached a peak level on day 42 and maintained this level to the end of the experiment. The current study suggests for the first time the pattern of immune response during Trypanosoma evansi infection as a preliminary step for production of high affinity antibodies.

Key words: Trypanosoma evansi, immunization, IgM, IgG, high affinity antibodies, immunoassays.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by El-Awad M. El Hassan
Articles by Omar A. Al-Jabr
Articles by Sabry M. El-Bahr
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Hassan EME, Al-Jabr OA, El-Bahr SM. Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. AJVS. 2021; 70(1): 1-6. doi:10.5455/ajvs.87098


Web Style

Hassan EME, Al-Jabr OA, El-Bahr SM. Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. http://www.alexjvs.com/?mno=87098 [Access: August 17, 2021]. doi:10.5455/ajvs.87098


AMA (American Medical Association) Style

Hassan EME, Al-Jabr OA, El-Bahr SM. Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. AJVS. 2021; 70(1): 1-6. doi:10.5455/ajvs.87098



Vancouver/ICMJE Style

Hassan EME, Al-Jabr OA, El-Bahr SM. Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. AJVS. (2021), [cited August 17, 2021]; 70(1): 1-6. doi:10.5455/ajvs.87098



Harvard Style

Hassan, E. M. E., Al-Jabr, . O. A. & El-Bahr, . S. M. (2021) Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. AJVS, 70 (1), 1-6. doi:10.5455/ajvs.87098



Turabian Style

Hassan, El-Awad M. El, Omar A. Al-Jabr, and Sabry M. El-Bahr. 2021. Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. Alexandria Journal of Veterinary Sciences, 70 (1), 1-6. doi:10.5455/ajvs.87098



Chicago Style

Hassan, El-Awad M. El, Omar A. Al-Jabr, and Sabry M. El-Bahr. "Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies." Alexandria Journal of Veterinary Sciences 70 (2021), 1-6. doi:10.5455/ajvs.87098



MLA (The Modern Language Association) Style

Hassan, El-Awad M. El, Omar A. Al-Jabr, and Sabry M. El-Bahr. "Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies." Alexandria Journal of Veterinary Sciences 70.1 (2021), 1-6. Print. doi:10.5455/ajvs.87098



APA (American Psychological Association) Style

Hassan, E. M. E., Al-Jabr, . O. A. & El-Bahr, . S. M. (2021) Pattern of Antibody Response to Trypanosoma evansi Infection: A step for production of high affinity antibodies. Alexandria Journal of Veterinary Sciences, 70 (1), 1-6. doi:10.5455/ajvs.87098





Most Viewed Articles
  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract & References

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract & References » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Most Downloaded
  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract & References » doi: 10.5455/ajvs.47290

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Most Cited Articles
  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333
    Cited : 10 times [Click to see citing articles]

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232
    Cited : 8 times [Click to see citing articles]

  • Effect of Dietary Replacement of Inorganic Zinc by Organic or Nanoparticles Sources on Growth Performance, Immune Response and Intestinal Histopathology of Broiler Chicken
    Mohamed El-Katcha, Mosad A. Soltan, M. El-badry
    AJVS. 2017; 55(2): 129-145
    » Abstract » doi: 10.5455/ajvs.266925
    Cited : 7 times [Click to see citing articles]

  • Molecular Characterization, Antimicrobial Susceptibility and Salt Tolerance of Aeromonas hydrophila from Fresh, Brackish and Marine fishes
    Basma Dahdouh, Ola Basha, Samy Khalil, Mahmoud Tanekhy
    AJVS. 2016; 48(2): 46-53
    » Abstract & References » doi: 10.5455/ajvs.208107
    Cited : 6 times [Click to see citing articles]

  • The Growth Promoting Effect of Beta-glucan in Comparison with Sodium Butyrate in Broiler Chicks
    Abd El-Salam F. El-Sawy, Zeynab Kh. El-Maddawy, Hawary S. Ibrahiem and El-Sadeq Bo-Ghazel
    AJVS. 2015; 44(1): 23-37
    » Abstract & References » doi: 10.5455/ajvs.163992
    Cited : 5 times [Click to see citing articles]