E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense

Abakpa S.a.v., Talabi A.o., Oyekunle M.a., Ajibola E.s., Adebiyi A.a., Mshelbwala F.m., Akintunde G.o., Daramola O.o., Adeleye O.e., Okandeji M.e..


Abstract
Summary: Animal African Trypanosomosis (AAT) is a devastating protozoan disease of animals and humans caused by Trypanosoma spp resulting in a great economic loss in the livestock industries, in the sub-sahara Africa. Cardiac troponin I is released from myocytes in both reversible and irreversible myocardial injuries. This study investigated the expression of cardiac troponin I (cTn I) in dogs experimentally infected with Trypanosoma congolense. Fifteen mongrel dogs of both sexes and with average body weights of 9.3 kg were divided into three groups (A, B and C). Dogs in group A were uninfected, group B were infected but untreated, while group C were infected and treated with Diminazene aceturate at a single dose of 3.5 mg/kg intramuscularly. The serum cTn I concentrations in infected dogs were elevated on days 1, 10 and 17 post-infection (pi). Serum cTn I concentrations in dogs that were infected and treated decreased on day 5 post-treatment (day 22 pi) compared to those that were infected but not treated. Post mortem and histopathological findings in the heart of a dogs that died of the disease in the infected but not treated group revealed no visible lesions. We concluded that the elevation of cTn I in Mongrel breed of dogs occurred without structural damage to cardiac muscles.

Key words: Key words: Cardiac troponin I, T. congolense, infection, pathology, dogs


 
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How to Cite this Article
Pubmed Style

S.a.v. A, A.o. T, M.a. O, E.s. A, A.a. A, F.m. M, G.o. A, O.o. D, O.e. A, M.e. O. Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. AJVS. 2020; 64(1): 123-128. doi:10.5455/ajvs.19984


Web Style

S.a.v. A, A.o. T, M.a. O, E.s. A, A.a. A, F.m. M, G.o. A, O.o. D, O.e. A, M.e. O. Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. https://www.alexjvs.com/?mno=19984 [Access: May 04, 2025]. doi:10.5455/ajvs.19984


AMA (American Medical Association) Style

S.a.v. A, A.o. T, M.a. O, E.s. A, A.a. A, F.m. M, G.o. A, O.o. D, O.e. A, M.e. O. Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. AJVS. 2020; 64(1): 123-128. doi:10.5455/ajvs.19984



Vancouver/ICMJE Style

S.a.v. A, A.o. T, M.a. O, E.s. A, A.a. A, F.m. M, G.o. A, O.o. D, O.e. A, M.e. O. Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. AJVS. (2020), [cited May 04, 2025]; 64(1): 123-128. doi:10.5455/ajvs.19984



Harvard Style

S.a.v., A., A.o., . T., M.a., . O., E.s., . A., A.a., . A., F.m., . M., G.o., . A., O.o., . D., O.e., . A. & M.e., . O. (2020) Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. AJVS, 64 (1), 123-128. doi:10.5455/ajvs.19984



Turabian Style

S.a.v., Abakpa, Talabi A.o., Oyekunle M.a., Ajibola E.s., Adebiyi A.a., Mshelbwala F.m., Akintunde G.o., Daramola O.o., Adeleye O.e., and Okandeji M.e.. 2020. Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. Alexandria Journal of Veterinary Sciences, 64 (1), 123-128. doi:10.5455/ajvs.19984



Chicago Style

S.a.v., Abakpa, Talabi A.o., Oyekunle M.a., Ajibola E.s., Adebiyi A.a., Mshelbwala F.m., Akintunde G.o., Daramola O.o., Adeleye O.e., and Okandeji M.e.. "Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense." Alexandria Journal of Veterinary Sciences 64 (2020), 123-128. doi:10.5455/ajvs.19984



MLA (The Modern Language Association) Style

S.a.v., Abakpa, Talabi A.o., Oyekunle M.a., Ajibola E.s., Adebiyi A.a., Mshelbwala F.m., Akintunde G.o., Daramola O.o., Adeleye O.e., and Okandeji M.e.. "Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense." Alexandria Journal of Veterinary Sciences 64.1 (2020), 123-128. Print. doi:10.5455/ajvs.19984



APA (American Psychological Association) Style

S.a.v., A., A.o., . T., M.a., . O., E.s., . A., A.a., . A., F.m., . M., G.o., . A., O.o., . D., O.e., . A. & M.e., . O. (2020) Elevation of Serum Cardiac Troponin I Concentraion in Dogs Experimentally Infected with Trypanosoma Congolense. Alexandria Journal of Veterinary Sciences, 64 (1), 123-128. doi:10.5455/ajvs.19984





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