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Original Article 


Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites

Nader M. Sobhy, Hend M. El-damaty, Yousry A. El-shazly.


Abstract
A total of thirty water buffalo calves at smallholder farm suffering from skin lesions and clinical signs compatible with mange were investigated clinically and parasitologically. The efficacy of three topical drugs with ivermectin in the treatment of psoroptes mites was investigated. Infested calves were randomly allocated into four groups (6 calves each) in addition to a positive control group. The four uncontrolled groups were treated with a single subcutaneous injection of ivermectin at the rate of 1mL/50kg body weight. Three groups were treated with different topical agents including benzyl benzoate 25%, crotamiton 10% and permethrin 5% once daily for two consecutive days. The number of live mites in skin scrapings was obtained before and after treatment for eight weeks. Severity of skin lesions was evaluated and scored. The synergistic effect of each topical agent with ivermectin were compared for eliminating mites, aiming to obtain the ideal treatment model. Mite counts of the treated animals with ivermectin plus permethrin were significantly (p < 0.05) lower than those of the ivermectin plus benzyl benzoate at 2 weeks post-treatment. The efficiency of ivermectin plus permethrin was found to be significantly more effective in the treatment of mange even in the first days after application compared with other groups. Topical permethrin with ivermectin injection is a good combination for treatment of psoroptes mites infestation in buffalo calves.

Key words: Psoroptes spp. mites, Ivermectin, Permethrin, Benzyl benzoate, Crotamiton


 
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How to Cite this Article
Pubmed Style

Sobhy NM, El-damaty HM, El-shazly YA. Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. AJVS. 2018; 56(1): 162-168. doi:10.5455/ajvs.288930

Web Style

Sobhy NM, El-damaty HM, El-shazly YA. Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. https://www.alexjvs.com/?mno=288930 [Access: May 03, 2025]. doi:10.5455/ajvs.288930

AMA (American Medical Association) Style

Sobhy NM, El-damaty HM, El-shazly YA. Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. AJVS. 2018; 56(1): 162-168. doi:10.5455/ajvs.288930


Vancouver/ICMJE Style

Sobhy NM, El-damaty HM, El-shazly YA. Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. AJVS. (2018), [cited May 03, 2025]; 56(1): 162-168. doi:10.5455/ajvs.288930


Harvard Style

Sobhy, N. M., El-damaty, . H. M. & El-shazly, . Y. A. (2018) Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. AJVS, 56 (1), 162-168. doi:10.5455/ajvs.288930


Turabian Style

Sobhy, Nader M., Hend M. El-damaty, and Yousry A. El-shazly. 2018. Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. Alexandria Journal of Veterinary Sciences, 56 (1), 162-168. doi:10.5455/ajvs.288930


Chicago Style

Sobhy, Nader M., Hend M. El-damaty, and Yousry A. El-shazly. "Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites." Alexandria Journal of Veterinary Sciences 56 (2018), 162-168. doi:10.5455/ajvs.288930


MLA (The Modern Language Association) Style

Sobhy, Nader M., Hend M. El-damaty, and Yousry A. El-shazly. "Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites." Alexandria Journal of Veterinary Sciences 56.1 (2018), 162-168. Print. doi:10.5455/ajvs.288930


APA (American Psychological Association) Style

Sobhy, N. M., El-damaty, . H. M. & El-shazly, . Y. A. (2018) Clinical Studies on the Efficacy of Different Topical Drugs with Ivermectin Injection in the Treatment of Egyptian Water Buffalo Calves Infested with Psoroptes Spp. Mites. Alexandria Journal of Veterinary Sciences, 56 (1), 162-168. doi:10.5455/ajvs.288930




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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    Egypt.

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