E-ISSN 2536-9520 | ISSN 1110-2047
 
2026, Vol: 91
91Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 03 Oct 2026
 


Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows

Samia M. Abd El-rheem, Mostafa S. Mahboob, Kamal K. Metwelly.


Abstract
Bovine metritis is a severe uterine inflammation occurring within 21 days postpartum, drastically reducing dairy herd fertility, milk yield, and overall economic profitability. Conducted from November 2024 to February 2025 at a commercial dairy herd under Egyptian subtropical conditions, this ethically approved study evaluated 247 multiparous Holstein cows. Animals diagnosed with clinical metritis were randomly assigned to eight treatment groups. The experimental design was to test standard doses of: Excede, Gentamox, Cobactan, Synulox, Penstrip, Amoxicillin, Borgal, and Gentacure. Statistical comparisons demonstrated that Excede yielded the highest efficacy, achieving a 96.9% cure rate, minimal days open (90.88 ± 3.01days), and a 41.3% conception rate from the first insemination. Gentamox closely followed as a highly effective alternative (89.2% cure rate; 99.90 ± 3.32 days open). Cobactan maintained high pregnancy rates (80.0% total conception) with a minimal milk withdrawal window, whereas Synulox, Penstrip, and Amoxicillin showed moderate efficiency. Conversely, Borgal and Gentacure performed poorly, displaying the lowest cure rates (71.4% and 50.0%) and prolonged days open, proving less practical due to extended withdrawal restrictions.

Key words: metritis, antibiotics, postpartum, Holstein cattle


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Samia M. Abd El-Rheem
Articles by Mostafa S. Mahboob
Articles by Kamal K. Metwelly
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

El-rheem SMA, Mahboob MS, Metwelly KK. Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. AJVS. 2026; 91(0): 499-508. doi:10.5455/ajvs.327582

Web Style

El-rheem SMA, Mahboob MS, Metwelly KK. Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. https://www.alexjvs.com/?mno=327582 [Access: October 18, 2026]. doi:10.5455/ajvs.327582

AMA (American Medical Association) Style

El-rheem SMA, Mahboob MS, Metwelly KK. Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. AJVS. 2026; 91(0): 499-508. doi:10.5455/ajvs.327582


Vancouver/ICMJE Style

El-rheem SMA, Mahboob MS, Metwelly KK. Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. AJVS. (2026), [cited October 18, 2026]; 91(0): 499-508. doi:10.5455/ajvs.327582


Harvard Style

El-rheem, S. M. A., Mahboob, . M. S. & Metwelly, . K. K. (2026) Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. AJVS, 91 (0), 499-508. doi:10.5455/ajvs.327582


Turabian Style

El-rheem, Samia M. Abd, Mostafa S. Mahboob, and Kamal K. Metwelly. 2026. Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. Alexandria Journal of Veterinary Sciences, 91 (0), 499-508. doi:10.5455/ajvs.327582


Chicago Style

El-rheem, Samia M. Abd, Mostafa S. Mahboob, and Kamal K. Metwelly. "Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows." Alexandria Journal of Veterinary Sciences 91 (2026), 499-508. doi:10.5455/ajvs.327582


MLA (The Modern Language Association) Style

El-rheem, Samia M. Abd, Mostafa S. Mahboob, and Kamal K. Metwelly. "Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows." Alexandria Journal of Veterinary Sciences 91.0 (2026), 499-508. Print. doi:10.5455/ajvs.327582


APA (American Psychological Association) Style

El-rheem, S. M. A., Mahboob, . M. S. & Metwelly, . K. K. (2026) Evaluation of the Clinical and Reproductive Efficiency of Systemic Antibiotic Protocols for Treating Postpartum Metritis in Dairy Cows. Alexandria Journal of Veterinary Sciences, 91 (0), 499-508. doi:10.5455/ajvs.327582




Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

    •
    Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

    •

    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110-204 ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

    email: ajvs@alexu.edu.eg
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information