E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif.

Abstract
This study aimed to evaluate the clinicopathological and immunological profiles of two pesticides widely used in Egypt, Lampcon and Saturn in rats. Thirty male Sprague Dawley rats divided into three groups each of 10 were used in this study. The first group received no treatment and served as control, the second group received Lampcon at a dose of 11.2 mg/kg body weight, and the third group received Saturn at a dose of 282 mg/kg body weight. The treatments were administrated daily via food for 60 successive days. Blood samples were collected for evaluating the selected hematological, biochemical and immunological parameters. The results of hematological variables implicated no significant effect on red blood cell parameters, but there was a significant leukopenia, lymphopenia and neutrophilia in both treated groups. The blood biochemical parameters showed a significant increase in serum levels of urea and enzymatic activities of ALT, AST and ALP. The findings of immunological studies clarified that Lampcon and Saturn induced oxidative stress in leukocytes and had immunosuppressive effects. The main histopathological alterations induced by Lampcon and Saturn included lymphoid depletion in lymphoid organs. Conclusion: The results from the study have shown that exposure of rats to Lampcon and Saturn pesticides pose many hematological, biochemical, and histopathological alterations in addition to immunotoxic effects. It is thus advisable that Lampcon and Saturn should be used with caution and at the recommended levels indicated by the producing company to ensure minimal exposure to these pesticides during domestic, veterinary, agricultural or industrial use.

Key words: Lampcon, Saturn, Lambda cyhalothrin, Thiocarbamate, Immunity, Rats.


 
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REFERENCES
Abdallah, F.B., Fetoui, H., Fakhfakh, F., Keskes, L. 2012. Caffeic acid and quercetin protect erythrocytes against the oxidative stress and the genotoxic effects of lambda-cyhalothrin in vitro. Hum. Exp. Toxicol. 31: 92-100. [DOI via Crossref]    [Pubmed]   
Ahmad, I., Shukla, S., Kumar, A., Singh, B.K., Patel, D.K., Pandey, H.P., Singh, C. 2010. Maneb and paraquat-induced modulation of toxicant responsive genes in the rat liver: comparison with polymorphonuclear leukocytes. Chem. Biol. Interact. 188: 566-579. [DOI via Crossref]    [Pubmed]   
ATSDR 2003. Agency for Toxic Substances and Disease Registry. Toxicological Profile for Pyrethrins and Pyrethroids. Report. Available at: http://www.atsdr.cdc. gov/to profiles/tp155.html.
Bancroft, J.D., Stevens, A., Turner, D.R. 1996. Theory and Practice of Histological Techniques. (4th eds.), Churchill Livingstone, New York, USA.
Banerjee, B.D., Seth, V., Bhattacharya, A., Pasha, S.T., Chakraborty, A.K. 1999. Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers. Toxicol. Lett. 107: 33-47. [DOI via Crossref]   
Basir, A., Khan, A., Mustafa, R., Khan, M.Z., Rizvi, F., Mahmood, F., Yousaf, A. 2011. Toxicopathological effects of lambda-cyhalothrin in female rabbits (Oryctolagus cuniculus). Hum. Exp. Toxicol. 30: 591-602. [DOI via Crossref]    [Pubmed]   
Brundage, K.M., Barnett, J.B. 2010. Immunotoxicity of Pesticides. In: "Hayes' Handbook of Pesticide Toxicology" (Krieger, R., 3rd eds), Academic Press/Elsevier, New York, USA, Pp: 483-497. [DOI via Crossref]   
Calviello, G., Piccioni, E., Boninsegna, A., Tedesco, B., Maggiano, N., Serini, S., Wolf, F.I., Palozza, P. 2006. DNA damage and apoptosis induction by the pesticide Mancozeb in rat cells: involvement of the oxidative mechanism. Toxicol. Appl. Pharmacol., 211: 87-96. [DOI via Crossref]    [Pubmed]   
Chauhan, R.S., Agrawal, D.K. 1999. Immunopathology of alphamethrin in bovine calves. Indian J. Animal Sci., 69: 556-559.
CPHG 2000. California Public Health Goal for Chemicals in Drinking Water. Thiobencarb. Prepared by Office of Environmental Health Hazard Assessment California Environmental Protection Agency Pesticide and Environmental Toxicology Section. Available at: http://oehha.ca.gov/water/phg/pdf/thioben.pdf.
Danneberg, A.M. 1991. Delayed-type hypersensitivity and cell mediated immunity in the pathogenesis of tuberculosis. Immunol. Today 12: 228–233. [DOI via Crossref]   
Dean, J.H., Cornacoff, J.B., Rosenthal, G.J., Luster, M.I. 1989. Immune system: Evaluation of injury. In: Principles and methods of Toxicology. Hayes A W (2nd Ed.), Raven Press, New York, Pp: 741- 760.
Diel, F., Detscher, M., Borck, H., Schrimpf, D., Diel, E., Hoppe, H.W. 1998. Effects of permethrin on human basophils and lymphocytes in vitro. Inflamm. Res., 47 (Suppl.1), S11–12. [DOI via Crossref]    [Pubmed]   
Duncan, J.R., Prasse, K.W., Mahaffey, E.A. 1994. Veterinary Laboratory Medicine: Clinical Pathology, 3rd ed. 1994, Lowa State, university press, Ames, Lowa.
Dutta, R., Das, N. 2011. Immunomodulation of serum complement (C3) and macrophages by synthetic pyrethroid fenvalerate: in vitro study. Toxicol. 285: 126-132. [DOI via Crossref]    [Pubmed]   
El-Demerdash, F.M. 2007. Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicol. In Vitro. 21: 392-397. [DOI via Crossref]    [Pubmed]   
El-Tawil, O.S., Abdel-Rahman, M.S. 1997. Effect of cypermethrin on isolated male and female rat hepatocytes. J. Toxicol. Environ. Health 52: 461–474. [DOI via Crossref]    [Pubmed]   
EPA (US Environmental Protection Agency) 1991. Data evaluation record: Esfenvalerate: Subchronic oral toxicity (90:day) mouse. US. Environmental Protection Agency, Office of Pesticide Programs. Tox. Rev., 008967.
Ercal, N., Neal, R., Treeratphan, P., Lutz, P.M., Hammond, T.C., Dennery, P.A., Spitz, D.R. 2000. A role for oxidative stress in suppressing serum immunoglobulin levels in lead-exposed Fisher 344 rats. Arch. Environ. Contam. Toxicol. 39: 251-256. [DOI via Crossref]    [Pubmed]   
Fahey, J.L., McKelvey, E.M. 1965. Quantitative determination of serum immunoglobulins in antibody-agar plates. J. Immunol. 94: 84–90. [Pubmed]   
Fan, A.M., Alexeeff, G.F. 2000. Public Health Goal for Thiobencarb In Drinking Water. California Environmental Protection Agency.
Feldman, B.F., Zinkl, J.C., jain, N.C. 2000. "Schalm's Veterinary Hematology", 5th (ed.), Lippincott Williams & Wilkins, Philadelphia, London.
Fetoui, H., Garoui, E.M., Makni-Ayadi, F., Zeghal, N. 2008. Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: Attenuation by vitamin C. Environ. Toxicol. Pharmacol. 26: 225-231. [DOI via Crossref]    [Pubmed]   
Gad, S.C. 2001. Statistics For Toxicologists. In: Principles and Methods of Toxicology, Hayes, A.W. 4th Ed, . Taylor & Francis, Philadelphia. Pp: 285 – 364.
Garg, U.K., Pal, A.K., Jha, G.J., Jadhao, S.B. 2004. Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. Int. Immunopharmacol. 4: 1709-1722. [DOI via Crossref]    [Pubmed]   
Griffin, K. 2012. Isolate leukocytes from whole blood. In Griffin Open Wetware at http://openwetware.org/wiki/Griffin; 2008: Isolate Leukocytes from whole blood. Accessed on April 13 2012.
Grosman, N., Diel, F. 2005. Influence of pyrethroids and piperonyl butoxide on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. Int. Immunopharmacol., 5: 263-270. [DOI via Crossref]    [Pubmed]   
Hassan, Z.M., Ostad, S.N., Minaee, B., Narenjkar, J., Azizi, E., Neishabouri, E.Z. 2004. Evaluation of immunotoxicity induced by propoxur in C57Bl/6 mice. Int. Immunopharmacol., 4: 1223-1230. [DOI via Crossref]    [Pubmed]   
IPCS INCHEM 1990. IPCS/International Programme on Chemical Safety. Health and safety guide no. 38. Cyhalothrin and lambda-cyhalothrin.
Ishmael, I., Litchfield, M.H. 1988. Chronic toxicity and carcinogenic evaluation of permethrin in rats and mice. Fund. Appl. Toxicol. 11: 308–322. [DOI via Crossref]   
Jaisson, S., DelevallĂ©e-Forte, C., TourĂ©, F., Rieu, P., Garnotel, R., Gillery P. 2007. Carbamylated albumin is a potent inhibitor of polymorphonuclear neutrophil respiratory burst. FEBS Lett. 581: 1509-1513. [DOI via Crossref]    [Pubmed]   
Khan, D.A., Bhatti, M.M., Khan, F.A., Naqvi, S.T., Karam, A. 2008. Adverse Effects of Pesticides Residues on Biochemical Markers in Pakistani Tobacco Farmers. Int. J. Clin. Exp. Med., 1(3): 274–282. [Pubmed]    [PMC Free Fulltext]   
Krishnappa, H., Honnegowda, Suresh, T.P., Jayakumar, K., Narayana, K. 1999. Effect of Lambda cyhalothrin, a synthetic pyrethroid insecticide on certain defense mechanisms and immune response in male rats. Ind. Vet. J. 76: 506-510.
Kuz'minskiÄ­, S.N., Popko, V.I. 1992. Immune reactivity disorders in poisoning by the pyrethroid sumi-alpha. Lik. Sprava., 9: 88-90. [Pubmed]   
Ladics, G.S., Smith, C., Heaps, K., Loveless, S.E. 1994. Evaluation of the humoral immune response of CD rats following a 2-week exposure to the pesticide carbaryl by the oral, dermal, or inhalation routes. J. Toxicol. Environ. Health 42: 143-156. [DOI via Crossref]    [Pubmed]   
Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685. [DOI via Crossref]    [Pubmed]   
Luty, S., Haratym:Maj, A., Latuszynska, J., Przebirowska, D.B., Rodak, M.K. 2001. Oral toxicity of deltamethrin and fenvalerate in swiss mice. Ann. Agric. Environ. Med., 8: 245–254.
Mancini, G., Carbonara, A.O., Heremans, J.F. 1965. Immunochemical quantitation of antigens by single radial immunodiffusion. Immun. Chem. 2: 235–254. [DOI via Crossref]   
Manna, P.R., Eubank, D.W., Lalli, E., Sassone-Corsi, P., Stocco, D.M. 2003. Transcriptional regulation of the mouse steroidogenic acute regulatory protein gene by the cAMP response:element binding protein and steroidogenic factor 1. J. Mol. Endocrinol. 30: 381–397. [DOI via Crossref]    [Pubmed]   
Matsushima, Y., Uchida, O. Saitoh, M., Kawasaki, Y., Isama, K., Kaniwa, M., Inoue, T., Kanno, J. 2003. Twenty:eight day repeated dose oral toxicity test of synergist of a pyrethroid insecticide, 2,3,3,3,2',3',3',3': Octachlorodipropyl ether (S:421) in rats. kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku, 121: 40-47.
Medjdoub, A., Merzouk, S.A., Merzouk, H., Chiali, F.Z., Narce, M. 2011. Effects of Mancozeb and Metribuzin on in vitro proliferative responses and oxidative stress of human and rat spleen lymphocytes stimulated by mitogens. Pest. Biochem. Physiol. 101: 27–33. [DOI via Crossref]   
Monis, B., Valentich, M.A. 1993. Promoting effects of mancozeb on pancreas of nitrosomethyl urea treated rats. Carcinogen.14: 929 – 933. [DOI via Crossref]   
Naravaneni, R., Jamil, K. 2005. Evaluation of cytogenetic effects of lambda-cyhalothrin on human lymphocytes. J. Biochem. Mol. Toxicol. 9: 304-310. [DOI via Crossref]    [Pubmed]   
Petrovova, E., Massanyi, P., Capcarova, M., Zivcak, J., Stodola, L. 2011. Structural alterations in rabbit spleen after bendiocarb administration. J. Environ. Sci. Health. B., 46: 788-792. [Pubmed]   
Petrovova, E., Mazensky, D., Luptakova, L., Holovska, K., Spalekova, E., Massanyi, P., Haladova, E., Toth T. 2010. Alterations in the rabbit lymphoid tissue after bendiocarb administration. J. Environ. Sci. Health B., 45: 719-728. [DOI via Crossref]    [Pubmed]   
Pipy, B., de Maroussem, D., Beraud, M., Derache, P. 1983. Evaluation of cellular and humoral mechanisms of carbaryl-induced reticuloendothelial phagocytic depression. J. Reticuloendothel. Soc. 34: 395-412. [Pubmed]   
Prater, M.R., Gogal, R.M., Blaylock, B.L., Holladay S.D. 2003. Cis-urocanic acid increases immunotoxicity and lethality of dermally administered permethrin in C57BL/6N mice. Int. J. Toxicol. 22: 35-42. [DOI via Crossref]    [Pubmed]   
Pruett, S.B., Cheng, B., Fan, R., Tan, W., Sebastian, T. 2009. Oxidative stress and sodium methyldithiocarbamate-induced modulation of the macrophage response to lipopolysaccharide in vivo. Toxicol. Sci. 109: 237-246. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
Righi, D.A., Xavier, F.G., Palermo-Neto, J. 2009. Effects of type II pyrethroid cyhalothrin on rat innate immunity: a flow cytometric study. Int. Immunopharmacol. 9: 148-152. [DOI via Crossref]    [Pubmed]   
Royal Society of Chemistry 1991. The Agrochemicals Handbook, Royal Society of Chemistry Information Services. Cambridge, UK. Cited by EXTOXNET (Extension Toxicology Network): Lambda cyhalothrin. A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis.
Saka, W.A., Akhigbe, R.E., Azeez, O.M., Babatunde, T.R. 2011. Effects of Pyrethroid Insecticide Exposure on Haematological and Haemostatic Profiles in Rats. Pak. J. Biol. Sci. 14(2): 1024-1027. [Pubmed]   
Sangha, G.K., Kaur, K., Khera, K.S., Singh, B. 2011. Toxicological effects of cypermethrin on female albino rats. Toxicol. Int. 18: 5-8. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
Saquib, Q., Al-Khedhairy, A.A., Singh, B.R., Arif, J.M., Musarrat, J. 2010. Genotoxic fungicide methyl thiophanate as an oxidative stressor inducing 8-oxo-7,8-dihydro-2' -deoxyguanosine adducts in DNA and mutagenesis. J. Environ. Sci. Health. B. 45: 40-45. [DOI via Crossref]    [Pubmed]   
Saxena, P., Saxena, A.K. 2010. Cypermethrin Induced Biochemical Alterations in the Blood of Albino Rats. Jordan J. Biological Sci. 3(3): 111 – 114.
Sayim, F., Yavasolglu, N.U.K., Uyanikgil, Y., Aktug, H., Yavasolglu, A., Turgut, M. 2005. Neurotoxic effects of cypermethrin in Wistar rats: a hematological, biochemical and histopathological study. J. Health Sci. 51: 300–307. [DOI via Crossref]   
Seinen, W., Vos, J.G., krieken, R.V., Penninks, A., Brands, R., Hooykaas, H. 1977. Toxicity of organotin compounds. III. Suppression of thymusdependent immunity in rats by di-n-butyltindichloride and di-noctyltindichloride. Toxicol. Appl. Pharmacol. 42: 213–224. [DOI via Crossref]   
SERA 2010. Syracuse Environmental Research Associates: Lambda-Cyhalothrin Human Health and Ecological Risk Assessment Final Report. Syracuse Environmental Research Associates, New York.
Sharaf, S., Khan, A., Khan, M.Z., Aslam, F., Saleemi, M.K., Mahmood F. 2009. Clinico-hematological and micronuclear changes induced by cypermethrin in broiler chicks: Their attenuation with vitamin E and selenium. Exp. Toxicol. Pathol. 62: 333-341. [DOI via Crossref]    [Pubmed]   
Sharma, R.P. 2005. Organophosphates, Carbamates, and the Immune System. In: "Toxicology of Organophosphate and Carbamate Compounds" (Gupta R.C., eds), Academic Press, USA, Pp. 495-507. [PMC Free Fulltext]   
Singh, B.P., Singhal, L., Chauhan, R.S. 2007. Immunotoxicity of carbaryl in chicken. Indian J. Exp. Biol. 45: 890-895. [Pubmed]   
Singhal, L.K., Bagga, S., Kumar, R., Chauhan, R.S. 2003. Down regulation of humoral immunity in chickens due to carbendazim. Toxicol. In Vitro. 17: 687-692. [DOI via Crossref]   
Sood, R. 2006. Medical laboratory technology method and interpretations Fifth Edition. Jaypee Brothers Medical Publishers (P)LTD. New Delhi pp723.
Suke, S.G., Kumar, A., Ahmed, R.S., Chakraborti, A., Tripathi, A.K., Mediratta, P.K., Banerjee, B.D. 2006. Protective effect of melatonin against propoxur-induced oxidative stress and suppression of humoral immune response in rats. Indian J. Exp. Biol. 44: 312-315. [Pubmed]   
Tomlin, C. 1994. The Pesticide Manual: Incorporating The Agrochemicals Handbook. 10th Ed., British Crop Protection Council. Blackwell Science Inc., USA.
US EPA 1988. US Environmental Protection Agency Fact Sheet Number 171: Karate (PP321). Washington, DC. Cited by EXTOXNET (Extension Toxicology Network): Lambda cyhalothrin. A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis.
US EPA RED 1997. United States Environmental Protection Agency Reregistration Eligibility Decision. Thiobencarb., List B. Case 2665, Washington.
Weil, C.S. 1952. Tables for convenient calculation of median effective dose (LD50 or ED50) and instructions in their use. Biomet. 8: 249- 263. [DOI via Crossref]   
Wilkinson, P.C. 1981. Techniques in clinical immunology. 2nd ed., Black well scientific publications, London., Pp. 287-288.
Yousef, M.I. 2010. Vitamin E modulates reproductive toxicity of pyrethroid lambda-cyhalothrin in male rabbits. Food Chem. Toxicol. 48: 1152-1159. [DOI via Crossref]    [Pubmed]   
Zaahkouk, S.A.M., Helal, E.G.E., Abd-Rabo, T.E.I., Rashed, S.Z.A. 2000. Carbamate Toxicity and Protective effect of vit. A and vit. E on some biochemical aspects of male albino rats. The Egyptian J. Hospital Med. 1: 60- 77.

How to Cite this Article
Pubmed Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. AJVS. 2016; 48(1): 76-86. doi:10.5455/ajvs.207603


Web Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. http://www.alexjvs.com/?mno=207603 [Access: August 17, 2021]. doi:10.5455/ajvs.207603


AMA (American Medical Association) Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. AJVS. 2016; 48(1): 76-86. doi:10.5455/ajvs.207603



Vancouver/ICMJE Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. AJVS. (2016), [cited August 17, 2021]; 48(1): 76-86. doi:10.5455/ajvs.207603



Harvard Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif (2016) Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. AJVS, 48 (1), 76-86. doi:10.5455/ajvs.207603



Turabian Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. 2016. Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. Alexandria Journal of Veterinary Sciences, 48 (1), 76-86. doi:10.5455/ajvs.207603



Chicago Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. "Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats." Alexandria Journal of Veterinary Sciences 48 (2016), 76-86. doi:10.5455/ajvs.207603



MLA (The Modern Language Association) Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif. "Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats." Alexandria Journal of Veterinary Sciences 48.1 (2016), 76-86. Print. doi:10.5455/ajvs.207603



APA (American Psychological Association) Style

Tamer S. Allam, Nahed S. Saleh, Emad W. Ghazy, Amera S. Abd El-Latif (2016) Effects of Sublethal Doses of Lampcon® and Saturn® Pesticides on Some Clinicopathological and Immunological Parameters in Rats. Alexandria Journal of Veterinary Sciences, 48 (1), 76-86. doi:10.5455/ajvs.207603





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