E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 85
85Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 12 Jun 2025
 


The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine

Azza M. Mohamed, Mohamed H. Atwa, Eman R. Abdo, Diana M. Abul Magd.


Abstract
In this work, a trial was conducted to improve sheep reaction of the immune system to the inactivated FMD vaccination by using Zylexis as an immune-modulatory. Three groups of five sheep each were formed from the fifteen sheep. The first group received 2 injections of zylexis (2 ml/sheep, I/M) given on three days interval concurrently with vaccination with one dose of the inactivated FMD (SAT-2) vaccine (1ml/sheep, S/C); the second group got the vaccination and nothing else, while the third group served as a control and did not get any inoculation at all. To evaluate the humeral immune response, SNT and ELISA were used to serum samples, and blood samples obtained while taking heparin as an anticoagulant to assess the cellular immune response. Over the course of 40 weeks after vaccination, the findings showed that sheep given the inactivated zylexis vaccine had a stronger cellular and humoral immune response than sheep given the inactivated FMD (SAT-2) vaccine alone. In order to prolong the duration of immunity, it might be suggested to combine it with FMD vaccination. This would boost the immunological response of vaccinated animals.

Key words: FMD, SAT-2, Zylexis, SNT, ELISA,


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Azza M. Mohamed
Articles by Mohamed H. Atwa
Articles by Eman R. Abdo
Articles by Diana M. Abul Magd
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS. Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075

Web Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. https://www.alexjvs.com/?mno=259075 [Access: June 19, 2025]. doi:10.5455/ajvs.259075

AMA (American Medical Association) Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS. Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075


Vancouver/ICMJE Style

Mohamed AM, Atwa MH, Abdo ER, Magd DMA. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS, [cited June 19, 2025]; Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075


Harvard Style

Mohamed, A. M., Atwa, . M. H., Abdo, . E. R. & Magd, . D. M. A. (0) The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. AJVS, Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075


Turabian Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. 0. The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. Alexandria Journal of Veterinary Sciences, Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075


Chicago Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. "The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine." Alexandria Journal of Veterinary Sciences Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075


MLA (The Modern Language Association) Style

Mohamed, Azza M., Mohamed H. Atwa, Eman R. Abdo, and Diana M. Abul Magd. "The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine." Alexandria Journal of Veterinary Sciences Online First: 12 Jun, 2025. Web. 19 Jun 2025 doi:10.5455/ajvs.259075


APA (American Psychological Association) Style

Mohamed, A. M., Atwa, . M. H., Abdo, . E. R. & Magd, . D. M. A. (0) The Role of Parapox virus (Zylexis) in Enhancing Humeral and Cellular Immune Response in Sheep Vaccinated with FMD Vaccine. Alexandria Journal of Veterinary Sciences, Online First: 12 Jun, 2025. doi:10.5455/ajvs.259075




Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

    •
    Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

    •
    Most Cited Articles
    Most Cited Articles

    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

    email: ajvs@alexu.edu.eg
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information