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2025, Vol: 85
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Original Article 


In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis

Rasha Mansour, Madiha S. Ibrahim, Hazem M. Shaheen.


Abstract
Salmonella enterica serovar enteriditis is a food borne pathogen of human causing food-poisoning and sometime deaths. Many methods have been carried out to decrease the population and prevalence of the causative agent, including chemotherapy and disinfection. In this study, in vitro combination between chemotherapy and disinfection was carried out. Three disinfectants [TH4®(combination of quaternary ammonium compound and gluteraldhyde), Povidone Iodine®(iodophore) and Virkon® S(peroxygen compound)] were tested in vitro against Salmonella enteritidis. The effect of disinfectants, concentration and time of exposure on the survival of Salmonella enteritidis was investigated.TH4 0.5%(w/v),Virkon S 1%(w/v) and Povidone iodine7.5%(w/v) reduced Salmonella enteritidis by 99.9%,72% and 87%, respectively. Further, as the disinfectants' concentration decreased, the survival of bacteria increased. Virkon S and Povidone Iodine recorded satisfied result at 10 min exposure time. TH4 recorded high results at 30 min exposure time. The in vitro combination between the three disinfectants and 10%Norfloxacin showed improvement of the inhibitory effect of TH4and Povidone Iodine, while the inhibitory effect of Virkon S decreased. In addition, formation of macroscopically white precipitation, which interfere with effect of the two (Virkon Sand norfloxacin 10%) and lead to bad inhibitory effect on Salmonella enteritidis.

Key words: Salmonella enteritidis, Disinfectants, TH4,Virkon-S,Povidone Iodine, Norfloxacin.


 
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How to Cite this Article
Pubmed Style

Mansour R, Ibrahim MS, Shaheen HM. In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. AJVS. 2018; 56(1): 110-116. doi:10.5455/ajvs.275828

Web Style

Mansour R, Ibrahim MS, Shaheen HM. In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. https://www.alexjvs.com/?mno=275828 [Access: March 25, 2025]. doi:10.5455/ajvs.275828

AMA (American Medical Association) Style

Mansour R, Ibrahim MS, Shaheen HM. In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. AJVS. 2018; 56(1): 110-116. doi:10.5455/ajvs.275828


Vancouver/ICMJE Style

Mansour R, Ibrahim MS, Shaheen HM. In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. AJVS. (2018), [cited March 25, 2025]; 56(1): 110-116. doi:10.5455/ajvs.275828


Harvard Style

Mansour, R., Ibrahim, . M. S. & Shaheen, . H. M. (2018) In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. AJVS, 56 (1), 110-116. doi:10.5455/ajvs.275828


Turabian Style

Mansour, Rasha, Madiha S. Ibrahim, and Hazem M. Shaheen. 2018. In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. Alexandria Journal of Veterinary Sciences, 56 (1), 110-116. doi:10.5455/ajvs.275828


Chicago Style

Mansour, Rasha, Madiha S. Ibrahim, and Hazem M. Shaheen. "In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis." Alexandria Journal of Veterinary Sciences 56 (2018), 110-116. doi:10.5455/ajvs.275828


MLA (The Modern Language Association) Style

Mansour, Rasha, Madiha S. Ibrahim, and Hazem M. Shaheen. "In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis." Alexandria Journal of Veterinary Sciences 56.1 (2018), 110-116. Print. doi:10.5455/ajvs.275828


APA (American Psychological Association) Style

Mansour, R., Ibrahim, . M. S. & Shaheen, . H. M. (2018) In Vitro Synergistic and/or Antagonistic Studies of Norfloxacin with Some Disinfectants Against Salmonella Enteritidis. Alexandria Journal of Veterinary Sciences, 56 (1), 110-116. doi:10.5455/ajvs.275828




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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