E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses

Ali M. Metwally, Zeinab K. Ebrahim, Ibrahim A. Abdullaziz.

Abstract
Equine exertional rhabdomyolysis (ER) is a well-recognized disease affecting racehorses therefore this study was performed to evaluate haemato-biochemical alterations in 20 adult Arabian horses after 120 km race with trial of treatment. Horses were classified into 2 main groups: the first group (n:5) included healthy control horses while the second group(n:15) included horses showed signs of distress, moderately depressed, muscle stiffness, shifting hind limb lameness, elevated respiratory rate, sweating, firm painful hindquarter muscles, myoglobinuria and reluctance to move that lasts for several hours after ending of race. Based on the history and the through clinical examination of diseased horses, they were tentatively diagnosed as suffering from ER syndrome. Whole blood and serum samples were collected from both healthy control horses and diseased ones before and after treatment. Hemogram of examined horses showed only significant increased PCV (%) values of diseased horses with more prominent thrombocytopenia but with treatment their values showed marked improvement, where other haematological parameters showed non-significant changes in both groups either before or after treatment. Serum analysis of ER affected horses showed a higher serum enzymatic activities of creatine phosphokinase (CK) and aspartate aminotransferase (AST) with significantly increased values of total proteins, albumin, globulins, total bilirubin, glucose, creatinine and potassium. But with effective treatment protocol, these higher values began to be improved towards normal values again. While non-significant changes were observed in serum levels of Gamma-glutamyl transpeptidase (GGT), calcium, sodium and blood urea nitrogen (BUN) in ER affected horses. Based on obtained results, ER has negative impact on haemato-biochemical biomarkers with remarkable serum elevation of skeletal muscular specific enzymes, as well as by paralytic myoglobinuria.

Key words: Exercise related myopathy, Endurance horses, Exertional rhabdomyolysis


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ali M. Metwally
Articles by Zeinab K. Ebrahim
Articles by Ibrahim A. Abdullaziz
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Metwally AM, Ebrahim ZK, Abdullaziz IA. Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. AJVS. 2022; 75(2): 138-143. doi:10.5455/ajvs.75


Web Style

Metwally AM, Ebrahim ZK, Abdullaziz IA. Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. https://www.alexjvs.com/?mno=75 [Access: December 06, 2023]. doi:10.5455/ajvs.75


AMA (American Medical Association) Style

Metwally AM, Ebrahim ZK, Abdullaziz IA. Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. AJVS. 2022; 75(2): 138-143. doi:10.5455/ajvs.75



Vancouver/ICMJE Style

Metwally AM, Ebrahim ZK, Abdullaziz IA. Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. AJVS. (2022), [cited December 06, 2023]; 75(2): 138-143. doi:10.5455/ajvs.75



Harvard Style

Metwally, A. M., Ebrahim, . Z. K. & Abdullaziz, . I. A. (2022) Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. AJVS, 75 (2), 138-143. doi:10.5455/ajvs.75



Turabian Style

Metwally, Ali M., Zeinab K. Ebrahim, and Ibrahim A. Abdullaziz. 2022. Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. Alexandria Journal of Veterinary Sciences, 75 (2), 138-143. doi:10.5455/ajvs.75



Chicago Style

Metwally, Ali M., Zeinab K. Ebrahim, and Ibrahim A. Abdullaziz. "Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses." Alexandria Journal of Veterinary Sciences 75 (2022), 138-143. doi:10.5455/ajvs.75



MLA (The Modern Language Association) Style

Metwally, Ali M., Zeinab K. Ebrahim, and Ibrahim A. Abdullaziz. "Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses." Alexandria Journal of Veterinary Sciences 75.2 (2022), 138-143. Print. doi:10.5455/ajvs.75



APA (American Psychological Association) Style

Metwally, A. M., Ebrahim, . Z. K. & Abdullaziz, . I. A. (2022) Hematological, Biochemical, and Skeletal Muscle Metabolic Responses to Exercise Related Myopathy in Endurance Horses. Alexandria Journal of Veterinary Sciences, 75 (2), 138-143. doi:10.5455/ajvs.75





Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

  • Most Cited Articles
    Most Cited Articles