E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs

Emmanuella A.O. Sogebi, Adeniran Adetunji, Oluwaseun S. Olatunji.

Abstract
This study evaluated the comparative effects of Acepromazine-Butorphanol and Acepromazine-Buprenorphine premedicants in Propofol-Isoflurane anaesthesized Nigerian indigenous dogs. Using a prospective cross-over blinded clinical study, six adult Nigerian indigenous dogs were randomly selected for two trials with one week ‘wash out’ period between each trial. Trial I and Trial II were premedicated with Acepromazine+Butorphanol (0.04mg/kg IM + 0.3mg/kg IM) and Acepromazine+Buprenorphine (0.04mg/kg IM + 0.03mg/kg IM) respectively. Anaesthesia was induced in the two trials with Propofol (4mg/kg IV) and maintained with Isoflurane 2% in 2 liters of Oxygen. Cardiopulmonary parameters were recorded at 15minute intervals for 180 minutes. Anaesthetic indices, analgesia and side effects of the drugs were also observed. The study showed no significant alterations (p>0.05) in the anaesthetic indices of dogs in the two protocols. There were significant increases in heart and pulse rates at 45min post premedication in Acepromazine-Buprenorphine compared to Acepromazine-Butophanol. Hypotension was observed in Acepromazine-Buprenorphine premedicated dogs with no-significant decrease in MAP from 60 minutes post premedication. The degree of analgesia achieved with Acepromazine-Butorphanol was moderate while that of Acepromazine-Buprenorphine trial was mild. It was concluded that, either Butorphanol or Buprenorphine can be used in combination with Acepromazine for premedication in Nigerian indigenous dogs. However, Acepromazine-Butorphanol combination appears to be a better choice of neuroleptanalgesic premedicant in dogs due to its anaesthetic advantage.

Key words: Isoflurane, Neurolept-analgesic, Nigerian breed of dogs, Propofol


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Emmanuella A.O. Sogebi
Articles by Adeniran Adetunji
Articles by Oluwaseun S. Olatunji
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Sogebi EA, Adetunji A, Olatunji OS. Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. AJVS. 2020; 65(1): 96-101. doi:10.5455/ajvs.77317


Web Style

Sogebi EA, Adetunji A, Olatunji OS. Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. http://www.alexjvs.com/?mno=77317 [Access: November 28, 2020]. doi:10.5455/ajvs.77317


AMA (American Medical Association) Style

Sogebi EA, Adetunji A, Olatunji OS. Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. AJVS. 2020; 65(1): 96-101. doi:10.5455/ajvs.77317



Vancouver/ICMJE Style

Sogebi EA, Adetunji A, Olatunji OS. Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. AJVS. (2020), [cited November 28, 2020]; 65(1): 96-101. doi:10.5455/ajvs.77317



Harvard Style

Sogebi, E. A., Adetunji, . A. & Olatunji, . O. S. (2020) Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. AJVS, 65 (1), 96-101. doi:10.5455/ajvs.77317



Turabian Style

Sogebi, Emmanuella A.O., Adeniran Adetunji, and Oluwaseun S. Olatunji. 2020. Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. Alexandria Journal of Veterinary Sciences, 65 (1), 96-101. doi:10.5455/ajvs.77317



Chicago Style

Sogebi, Emmanuella A.O., Adeniran Adetunji, and Oluwaseun S. Olatunji. "Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs." Alexandria Journal of Veterinary Sciences 65 (2020), 96-101. doi:10.5455/ajvs.77317



MLA (The Modern Language Association) Style

Sogebi, Emmanuella A.O., Adeniran Adetunji, and Oluwaseun S. Olatunji. "Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs." Alexandria Journal of Veterinary Sciences 65.1 (2020), 96-101. Print. doi:10.5455/ajvs.77317



APA (American Psychological Association) Style

Sogebi, E. A., Adetunji, . A. & Olatunji, . O. S. (2020) Comparison of Two Neurolept-Analgesics Agents on Propofol-Isoflurane Anaesthesized Nigerian Indigenous Dogs. Alexandria Journal of Veterinary Sciences, 65 (1), 96-101. doi:10.5455/ajvs.77317





Most Viewed Articles
  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract & References

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract & References » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Most Downloaded
  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract & References » doi: 10.5455/ajvs.47290

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Most Cited Articles
  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333
    Cited : 10 times [Click to see citing articles]

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232
    Cited : 8 times [Click to see citing articles]

  • Effect of Dietary Replacement of Inorganic Zinc by Organic or Nanoparticles Sources on Growth Performance, Immune Response and Intestinal Histopathology of Broiler Chicken
    Mohamed El-Katcha, Mosad A. Soltan, M. El-badry
    AJVS. 2017; 55(2): 129-145
    » Abstract » doi: 10.5455/ajvs.266925
    Cited : 7 times [Click to see citing articles]

  • Molecular Characterization, Antimicrobial Susceptibility and Salt Tolerance of Aeromonas hydrophila from Fresh, Brackish and Marine fishes
    Basma Dahdouh, Ola Basha, Samy Khalil, Mahmoud Tanekhy
    AJVS. 2016; 48(2): 46-53
    » Abstract & References » doi: 10.5455/ajvs.208107
    Cited : 6 times [Click to see citing articles]

  • The Growth Promoting Effect of Beta-glucan in Comparison with Sodium Butyrate in Broiler Chicks
    Abd El-Salam F. El-Sawy, Zeynab Kh. El-Maddawy, Hawary S. Ibrahiem and El-Sadeq Bo-Ghazel
    AJVS. 2015; 44(1): 23-37
    » Abstract & References » doi: 10.5455/ajvs.163992
    Cited : 5 times [Click to see citing articles]